Computed Tomography(CT) is one of the key technologies in contemporary medical image and nondestructive testing. The art of medical CT is evolving rapidly and the last years have seen micro-CT systems with flat-panel detectors. These tomographs are able to collect high resolution three-dimensional datasets of small samples. Flat-panel micro-CT systems have merits of high-resolution, easier in image processing, smaller cubage, lower dose, etc.; which make the systems perfect for scanning small samples in medical images.Based on a micro-CT prototype, key technologies in designing flat-panel micro-CT systems have been researched here. Projective method has been applied for measuring the accurate position of X-ray source relative to the flat-panel detector. Because the detector is combined with two CCD instruments, a mathematic method is founded here to measure the otherness of the two CCD. To the question of fixed platform of micro-CT systems, cone-beam reconstruction formulas with a nonstationary shift of X-ray source are represented .Voltage of X-ray source used here is 10~35 kV, hard-beam effect is measured and adjusted in cone-beam reconstruction algorithms. To make reconstruction more rapidly with non-decreased image quality, half-scan FDK algorithm has been applied in software. Through micro-CT collecting projective images of samples, the software can reconstruct any part of three-dimensional dataset of samples with normal personal computers. Slice images and visualization of three-dimensional datasets showed the good performance of the micro-CT system and the capability of scanning small samples with high resolution.
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