| According to the need of medicine pelletisation, a New-style Miniature High Shear Granulator (MHSG)is designed, which is a kind of automatic pharmacy equipment to mix, to wet, to granulate at one time. This equipment includes Mechanical Configuration and Measuring and Controlling System. For technologic needs, the experiments present the relevant data corresponding different composition. Compared with a process operating by hand, the equipment shows high automation and efficiency, its product have proportioned granule in shape, similitude granularity in size. To this day, the equipment mode has been finished at whole, which program has become combining production between the measurement and control technology and the biochemistry engineering technology.The paper's content includes four aspects as follows:1. Having introduced the principle of MHSG, and according to technologic needs, finishing the Mechanical Configuration design, machining and fixing, including the shape and relevant position of impeller and chopper, the joint of impeller and mixing motor, and the joint of chopper and cutting motor;2. Having designed the automatic controlling scheme, including the controlling circuit design based on the ATmega32, PCB design and software design, implementing the real-time measure of temperature in mixing vessel, the testing and controlling of impeller and chopper speed;3. Having implemented the communication between controlling board and PC, designed the interface between human and computer adopting LabVIEW, which displays the parameters such as temperature, motor speed and time, in order to favor data storage and analysis;4. Aiming at the characteristic of different materiel, having finished the experiment and data analyze, and eventually confirmed the operation flow. |