Epidemiological Investigation Of Mixed Infection Of Pig Respiratory Tract In Some Large - Scale Farms In Eastern

Nowadays, with the development of intensive pig farming in Sichuan Province, large-scale cases of swine farms are becoming increasingly complex. Since 2010, large-scale pig farms in the eastern region of Sichuan respiratory mixed infection is particularly serious. This is due to the diversity of respiratory pathogens, clinical production in the two or more kinds mixed infections caused by pathogenic synergy. Studies have shown that at home and abroad, blue ear, ring type 2, pseudo rabies, swine fever and other easily lead immunosuppressive viruses are the main factors causing mixed infection, immunosuppressive virus first infects the body, the immune suppression for other viruses and bacteria the invasion opened the door. Therefore, understanding the variety of a link between viruses and bacteria for the prevention and treatment of mixed infections such diseases become particularly important. The survey by serological survey and pathogen detection combined to understand the scale farms in eastern Sichuan region porcine respiratory mixed infection prevalence, analysis of new trends in mixed infections, for future diagnosis, cure and prevention of respiratory tract infections in pigs mixed infections disease provide a reference.The findings are as follows:One pair of 585 samples,224 samples of classical swine fever antibodies copies antibody positive rate was 38.29%; porcine circovirus antibody positive samples of 276 copies, the antibody positive rate was 47.17%%; PRRS virus antibody positive samples 354 copies of the antibody positive rate was 60.51%; swine pseudo rabies virus antibody 162, antibody positive rate was 27.69%, the survey results indicate that a number of farms in the region does not meet sterility immunization effect the desired results, suspicion existed previously immunized virus infection.2 For 2012.3 month period from March 2014 to the region 13 large-scale pig farms totaling 183 mixed infection of the respiratory tract tissue disease death dead pig feed, perform PRRSV, CSFV, PRV, PCV2, APP, SS, PM, HPS, MHP, a total of nine kinds of pathogen detection.183 sick compound, eight kinds of pathogens were detected 172 positive samples. Eight cases of HPS cases in which positive detection rate of 4.37%; APP positive in 3 cases, the detection rate was 1.64%; SS positive in 3 cases, the detection rate was 1.69%; MHP positive 0 cases, the detection rate was 0%; PM positive case detection rate of 0.55%; PRRSV nucleic acid positive 73 cases, the detection rate was 39.89%; CSFV nucleic acid positive in 22 cases, the detection rate was 10.11%; PCV-2 nucleic acid positive in 58 cases, the detection rate of 22.40%; PRV nucleic acid-positive detection rate of 13 cases of 7.87%. The survey found that large-scale pig farms in the area of positive samples, the sample single infection caused by a single pathogen, only seven cases of death, the detection rate was 3.83%, while the mixing of two or more than two multi-pathogenic porcine respiratory disease caused by infection mixed infection was prevalent in a number of areas in the eastern part of large-scale pig farms in Sichuan, pathogen detection of tissue samples, the 172 positive samples in 165 parts of mixed infection, accounting for 95.93% of all positive samples. The main types of mixed infection with a virus or virus hybrid dual mixed with viral and bacterial infections based, there is a considerable portion of the sample or even triple or quadruple mixed infection. A sample of several pathogens simultaneously detected in a pig exist several pathogens, which fully shows that the region caused by porcine respiratory pathogens many types of mixed infections, the type of mixed infection complicated.