| This experiment regards the ARBAS white cashmere goats in Inner Mongolia as study materials. We cut skins monthly to study their hair follicles change in a year, making use of the Sacpic dying method to study horizontal, perpendicular slices. From horizontal slices we find that secondary follicles (SFs) enter into pro-anagen from May to August gradually. New pro-anagen follicles rebuild from old follicles. From August to December, they enter into anagen. Most of them enter into catagen in January. The period from February to April is their telagen. The perpendicular slices show that SFs' depth is the most deep in August and September and the breadth of bulbs and hair germs are most wide in October. In catagen SFs still have activity, but cashmeres grow slowly. In telagen SFs lose their activity and cashmeres no longer grow. In anagen, bulbs are flat and dermal papilla cells(DPC) sink inside. In catagen and telagen bulbs are sharp and DPCs are outwardly. The measuring result shows that cashmeres grow out skin earliest in June and grow fast in October in a year, but October is not the coldest month. The time of cashmeres growing out of skin is different individually, even different at every part in same individual. Cashmeres grow out from hip firstly, then from the side of the body, finally from shoulder.We construct cDNA library during anagen with skin in October and choose some clones randomly to gain sequences with M13(+) prime and obtain 636 ESTs. Alignment with Blastn database of Genebank, we find that the similarity of 41 ESTs among them to sheep KAP6-1 is more than 95% and the expectation is less than le-10. Further analysis we find that 41 full length cDNAs of KAP6 can be classified 6 different clusters. We choose a sequence from every cluster. Among them one sequence is same to sheep KAP6-1, but the other 5 sequences have slight difference. These results show that KAP6 household contain several members to participate in hair and cashmere's growth.
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