The Influence Of Different P-amino Phenylarsonic Acid Added Levels On Immune Organs Development And Immune Functions In Chickens

Arsenicum is one of the necessary trace elements in the body,and plays roles in many aspects.Meanwhile,arsenicum would do toxicity to the body if overdose is used.The experiment was conducted to study the influence of different added dose of PAPAA(P-amino phenylarsonic acid)in feed on immune organs development and immune functions,as well as the best added dose.The indexes including body weight performance,the immune organs indexes,immune functions,antioxidant functions and erythrocyte fragility and so on were measured in order to clarity the mechanicsm of PAPAA.In the experiment,280 hai-lanhe male healty chickens of 1-day-old were randomly divided into 7 groups.The control group was fed with basal diet,the test groups were fed with basal diet supplemented with 50,100,150,200,250,300mg/kg PAPAA respectively.70 days later,growth performance,the immune organs indexes,the charcoal clearance index,the lysozyme content in serum,ND antibody titer,the globulin content in serum,the rate of ANAE+ lymphocyte,the rate of lymphocyte transformation,activities of super-oxide dismutase (SOD) and glutathione peroxidase(GSH-PX),ability of total antioxidation function(T-AOC),the malondiadehyde(MDA)content in serum and the haemolytis rate of erythrocyte in different NaCl concentration were measured. Results were summarized as follows:1 Compared with the control group,the average body weighet and everyday gain of the test groups increased by 5.57%,7.97%,9.07%,13.77%,12.02%,8.96% respectively,and the group fed with 200mg/kg added level had the hightest body weight and everyday gain. The group fed with 200mg/kg added level had the highest immune organs indexes.