Clinical Observation Of Weikangning Decoction In Treating Functional Dyspepsia With Cold And Heat

Objective:In this study patients with functional dyspepsia mixed cold and heat type as the research object, observe the clinical efficacy and safety of Weikangning.Methods:This study comes from the hospital preparation Wangjing Hospital. A self controlled method for clinical trials met the inclusion criteria included 66 patients. Inclusion criteria:Western Roman III reference standards, reference 2009 TCM Chinese Medical Association Professional Committee of Medical stomach disease "functional dyspepsia Chinese medical consensus opinion ", "Chinese medicine clinical research guidelines Edition 2002 " in the "Chinese medicine treatment ruffian full clinical research guidelines " to develop. To Wangjing Hospital, Chinese Academy of Oral and stomach disease on therapy department self side "Weikangning " (ginger Pinellia 9g, skullcap 9g, Kawatsure 5g, ginger 9g, licorice 9g, fried white peony 15g, wide turmeric 9g, thick Park 9g, vinegar Xuan Hu lOg, Bupleurum 9g, rhubarb 6g, fried almonds 9g, Amomum 6g, Codonopsis 15g, jujube 4) a day before, Shuijianbi breakfast 30min,30min before going to sleep after each taking warm decoction 150ml; medication seven days for a course of four successive courses of treatment, observation period of 28 days, by observing the control patients before and after treatment of traditional Chinese medicine and Western medicine Syndrome symptom index markers, and safety evaluation, assessment "Weikangning side " of efficacy and safety.Results:The patients excluded because of lost six cases shedding caused, completed a total number of cases of clinical observation of 60 cases.Comparison of efficacy of clinical symptoms:1, TCM Syndrome Classification quantization table effect:two weeks of treatment, the total effective rate was 55.67%, effective rate is 5.00%; 4 weeks of treatment, the total effective rate was 88.3%, effective rate is 60%(P<0.05). TCM Syndrome patient’s degree of integration and individual scores before and after the differences were statistically significant(P<0.01).2, Western symptomatology grading scale effect:two weeks of treatment, the total effective rate was 63.33%, effective rate is 6.67%; 4 weeks of treatment, the total effective rate was 90.00%, effective rate is 65.00%(P<0.05). Western symptomatology scores and degree of the patient’s individual differences were statistically significant (P<0.01) scores before and after.3, Anxiety and Depression Scale:A total of 15 cases of patients with anxiety, the scores before and after treatment, Z=-4.676, P= 0.000 (P<0.05), a total of 10 cases of patients with depression, the scores before and after treatment, Z= 3.681, P=0.000 (P<0.05); differences were statistically significant.4, the safety evaluation:60 cases of security checks before and after treatment in patients with non-specific changes, to prove "Weikangning party" safe and reliable.Conclusion:"Weikangning party" for cold and heat mixed type of functional dyspepsia satisfactory outcome can relieve symptoms, which, on the upper abdominal pain, epigastric burning sensation and other symptoms significant effect, can relieve the patient of depression, depression, improve living quality, convenient and safe, no significant adverse reactions, worthy of clinical application.