A Systematic Review Of The Relationship Between TCM Syndrome Differentiation And Blood Lipid In Essential Hypertension

Objective:Systematic review method was used to get objective blood lipid-indicators for every syndrome in Essential Hypertension, and to estimate the relationship between TCM syndrome differentiation of Essential Hypertension and blood lipid.Methods:retrieve medical journals published in China and literature from1990to2013concerning clinical observation for relationship between TCM syndrome differentiation of Essential Hypertension and blood lipid in THTF CNKI Series Database, VIP Database of Chinese Journals and Wan fang Database of academic dissertations. By making use of NOS Quality Scale to choose literature and extract data and information, and applying REVMAN5.2software, meta analysis was made.Results:in accordance with the inclusive criteria,10articles were chosen. According to NOS Quality Scale,10articles were all evaluated as3stars and above. Merging value of blood lipid cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol of hypertension group and normal group showed significance in statistics, and the bounds of95%CI were greater than zero. Merging value of triglycerides from excessive phlegm-dampness syndrome&Ying deficiency and Yang excess syndrome and excessive phlegm-dampness syndrome&Ying&Yang deficiency syndrome showed significance in statistics, and the bounds of95%CI were greater than zero. Merging value of high density lipoprotein from excessive phlegm-dampness syndrome&liver-fire hyperactivity syndrome showed significance in statistics, and the bounds of95%CI were lower than zero. Merging value of low density lipoprotein from excessive phlegm-dampness syndrome&liver-fire hyperactivity syndrome and excessive phlegm-dampness syndrome&Ying deficiency and Yang excess syndrome showed significance in statistics, and the bounds of95%CI were greater than zero. Merging value of low density lipoprotein from Ying&Yang deficiency syndrome&liver-fire hyperactivity syndrome and Ying&Yang deficiency syndrome&Ying deficiency and Yang excess syndrome showed significance in statistics, and the bounds of95%CI were greater than zero.Conclusion:blood lipid rising rate of hypertension group was higher than that of normal group, therefore, blood lipid value could be regarded as one objective indicator of hypertension syndrome differentiation. Rising value of triglycerides and low density lipoprotein could be regarded as the objective indicator of excessive phlegm-dampness syndrome. Reducing value of high lipoprotein could be regarded as the objective indicator of excessive phlegm-dampness syndrome, Rising value of low density lipoprotein could be regarded as the objective indicator of Ying&Yang deficiency syndrome. Hence, this study would enrich TCM diagnostics further, and confirm that excessive phlegm-dampness syndrome and Ying&Yang deficiency syndrome were the basic pathology of "changes caused by eating fat meat and fine grain". Because some of the literature and journals retrieved in this study were with low grade in quality scale and some of them were a bit of peculiar, the conclusion of this study would be verified by experiments with large sample, multicenter, and rigorous design.