A Meta - Analysis Of The Effect Of Integrated Traditional Chinese And Western Medicine On The Recovery Time Of Biochemical Markers Of Acute

Objective: To use meta analysis and evaluation of Chinese and western medicine combined therapy of acute pancreatitis and biochemical index of recovery time. And according to the literature of traditional Chinese medicine(TCM) roughly commonly used drugs and methods for the treatment of acute pancreatitis.Methods: With "acute pancreatitis" or "abdominal pain" or "spleen heartache" or "despair an illusion of spleen" and "traditional Chinese medicine" or "integrative medicine" for the search term, in the China journal full-text database(CNKI) retrieve published in recent 10 years relevant clinical reports about the combination of traditional Chinese and western medicine treatment of acute pancreatitis. Develop literature inclusion and exclusion criteria, selection contains a randomized controlled trial(RCT) of clinical research, try to select diagnostic criteria and indicators of selected literature broadly similar evaluation standards of recovery, to minimize the clinical heterogeneity. According to the Jadad score standard of literature evaluation. Stats Direct software was used to meta analysis, according to the literature research variation situation choose fixed effects model or random effects model, using the weighted mean differences(WMD) and their 95% confidence interval(ci) said intervention results.Results: According to exclude and include standard, conform to the standard of clinical literature 14, a total of 1148 patients, western medicine routine treatment of 565 cases, combining Chinese and western medicine therapy for 583 cases, 14 articles were the object of study basic situation no significant statistical difference. Literature, according to the quality score 3 points 3, article 11 two points in this paper. The meta-analysis of the literature of 14 selected. Analysis results show:1. In terms of influence blood amylase, merge WMD =-1.32, 95% confidence interal,-1.60—-1.02, merge WMD hypothesis test z =-8.99, P < 0.0001. 2.In terms of influence urinary amylase, merge WMD =-1.52, 95% confidence interal,-2.09—-0.95, the merger of WMD hypothesis test z =-5.21, P < 0.0001. 3.In terms of influence blood leukocytes, merge WMD =-1.29, 95% confidence interal,-1.60—-0.96, merge WMD hypothesis test z =-7.82, P < 0.0001. 4.In terms of protein C- reaction, combination of WMD =-1.46, 95% confidence interal,-1.82—-1.10, merge WMD hypothesis test z =-7.99, P < 0.0001. 5.In the aspect of affecting blood lipase, merge WMD =-1.89, 95% confidence interal,-2.29—-.50, merge WMD hypothesis test z =-9.50, P < 0.0001, the difference was statistically significant.Conclusion: Combine traditional Chinese and western medicine therapy is pure western medicine treatment shorten recovery time AP and biochemical indicators.