The Study Of Fluorquinolones Antibiotics In The Vegetable Of Guangzhou And Dongguan

Antibiotics used extensively by human and animals could enter into the environment at last, which has been one of new-style contaminants and became the new research subject.Animal manure containing antibiotics is applied to agricultural land as a means to provide crop nutrients. As a result,the soil,even the produces grown on manure-amended soils could be contaminated. And these results could cause the same human health risk as drug residues(for animal food) and pesticide residues(for vegetable crops or plant food ).This article researched fluorquinolones concentration in the vegetables of the Guangzhou supermarket and the Dongguan vegetable fields and did the study on the preliminary evaluation of its health risk safety.The main conclusions were as follows:(1) An effective and low-cost analytical method for the simultaneous determination of four quinolones in vegetable was developed.Recoveries were in the range64.4%-116.9%;limits of detection were in the range 0.59～1.54μg/kg(dry weight);limits of quality were in the range 1.96～5.13μg/kg(dry weight )(2) This method was applied to analysis 3 fluorquinolones(Ciprofloxacin,Lomefloxacin and Enrofloxacin ) in the plants of supermarket in Guangzhou.The total concentration of 3 fluorquinolones in plants ranged from non-detected(ND) to 159.49μg/kg(fresh weight).The detection rate of fluorquinolones in all the samples was decreasing in order of Lomefloxacin (70%)＞Ciprofloxacin(69%)＞Enrofloxacin(29%).(3) This method was also applied to analysis 3 fluorquinolones(Ciprofloxacin,Lomefloxacin and Enrofloxacin ) in the plants of Dongguan vegetable fields.The total content of 3 fluorquinolones(Ciprofloxacin,Lomefloxacin and Enrofloxacin) in the plant ranged from ND to 255.67μg/kg(fresh weight),deceasing in the order of Shijie＞Tangsha＞Qiaotou1＞Chashan＞Dongcheng＞Qiaotou2 and non-social effects vegetable field＞common vegetable field.(4) This article did the study on the preliminary evaluation of its health risk safety,using the above-mentioned results.The ultra-standard rate of Ciprofloxacin and Enrofloxacin in plants of Guangzhou supermarket and Dongguan vegetable fields were 18.1%and 18.5%respectively and their times of ultra standard were 3.63 and 3.43 respectively.The levels of intakes with Ciprofloxacin and Enrofloxacin in plants of Guangzhou supermarket and Dongguan vegetable fields were 17.5%and 28.58%respectively. In short,pollution of Ciprofloxacin and Enrofloxacin in plant food is very serious,so the relevant control strategy should be adopted as quickly as possible in order to guarantee the safety of vegetable food.