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The Experiment Of Baicalin Extraction And Its Effects On Several Common Virus Of Swine And Chickens

Posted on:2011-03-31Degree:MasterType:Thesis
Country:ChinaCandidate:J C WangFull Text:PDF
GTID:2143360308985384Subject:Veterinarians
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As China's reforming and opening-up deeply and the rapid development of animal husbandry and the widespread circulation of livestock and poultry products, livestock infectious diseases occur is expanding trend. In order to prevent the occurrence of these diseases and targeting livestock products yield increase,Chemical synthetic drugs, antibiotics, hormones and prohibited drug are applied to practice, resulting in animal of food contamination are double threated by pathogens and veterinary drug residues. From a food safety perspective, traditional Chinese medicine from natural, side effects, drug safety, indeed, has a higher value in veterinary production..Scutellaria baicalensis Georgi for botanical drying root。In spring, autumn quarter mined, The bitter cold, moral character, to the lungs, heart, liver, large, With heat and dampness, purging fire Detox, Hemostatic, tocolysis. The ingredients have scutellaria baicalensis, skullcap, Han baicalin, Han scutellaria baicalensis new levels of, Go to a wogonin-, 7-methoxy baicalein, 7-methoxy-Han baicalein, etc., In addition there are volatile, benzene, ethanol glycosides. Where baicalin is the main drug ingredient skullcap. Many experimental proof, baicalin have antagonistic Microbe, enhance immunity, antipyretic, sedation, blood pressure, blood lipids, choleretic and antispasmodic, antioxidant, etc.This experiment selects scutellaria baicalensis, which approach its effect on immune function of swine and common viruses of chick embryo by extracting. As the follows:1. In order to find a best of extraction method, used by the industrialization of production by comparison of several extraction means; 2.To observe the vitro effection on porcine Parvovirus (PPV) by baicalin, evaluation its efficacy, to prevent and control pig of Parvovirus, providing scientific reference; 3.Extracting baicalin, observation the effect on chicken embryos of several common viral, understanding the effection of anti-viruses , providing a scientific reference for the poultry industry. At the same time, the three experimental datas give scientific theory to the production of antiviral drugs.The experiments get sever conclusions as follows: 1.During the three methods, baicalin yields vary greatly and reflux highest, but decoction and percolation is similar to a minimum.2.The vitro experiment of baicalin effect on porcine Parvovirus caused by CPE PPV after baicalin and PK-15 cells effecting.3.Extracting baicalin, observation its effections on chicken embryos, found that AIV, scutellaria baicalensis NDV, IBV is also inhibited.The results show: three extraction methods in yield are very different, but reflux is highest, decoction and percolation method is similar. Integrated these elements, you can see the obversly blocking effection coused caused by CPE PPV after baicalin and PK-15 cells effects ,which can be used to reference porcine Parvovirus medication. Extract baicalin, observation its effections on chicken embryos, found that AIV, scutellaria baicalensis NDV, IBV are also inhibited, shows baicalin are also valuable for disease prevention and treatment. Together, the role of a wide range of chicken, pork, non-toxic side effects, fully suited for plant production..
Keywords/Search Tags:baicalin, extraction, chicken embryo, viruses, PPV, AIV, NDV, IBV
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