Sulfonation Of Polyethersulfone And Its Adsorbent Microspheres

The mechanisms of various sulfonation methods for polyethersulfone (PES) and the applications of the sulfonated products were summarized in this thesis. A modified industrial sulfonation process with gaseous SC>3 in 1,2-dichloroethane as sulfonation agents, which was easily operated and cost effectively, was developed. Factors which effect the quality of sulfonated PES are complex solvent system, sulfonation agents, PES concentration, time and the manner of gaseous 863 distribution to the PES solution during sulfonation.An improved conductometric titration which is the combination of conductometry, acid-alkali volumetric determination and reverse titration in nonaqueous solvent, with which the quantities of free vitriol and sulfonation degree (D.S.) of SPES could be measured accurately and quickly, was proposed. Using Group Contribution method, the solubility parameters (Hansen parameters) of PES and SPES at various D.S. were estimated; the Group Contribution components of sulfone group and 1,2,4-trisubstitutional benzene group were complemented; and the mathematical model for estimating the polar component of Hansenparameters of polymers was put forward as well. In addition, a new nonlinear mathematical model for calculation solubility parameters of mixed solvents was proponed.The present of adsorbents for medical application, which were used most to purify blood or plasma via hemoperfusion or plamaperfusion, was also summarized in this thesis. PES and SPES microspheres with diameter from several um to several mm were prepared using apparatus designed. The structure of the microspheres was observed adopting tissue slice techniques, which showed that its exterior is compact and its interior is dentritic porous channels. Meanwhile, the mechanism of the form of vacuole microspheres was discussed for the first times as well.The static adsorptive experiments using various microspheres obtained in this thesis for removing methylene blue(MB) which had been widely used as virus inactive agents to induce photochemical damage of toxicological substrates, and had potential toxicity as well, was investigated. The result showed that SPES vacuole microspheres were better than PES both in adsorption rate and adsorbability; the adsorption rate increased along with the decrease of the diameter of hollow microspheres.