Evaluation Of Quality Of Life Pre And Post Interventional Therapy In Patients With Primary Hepatocellular Carcinoma And Analysis Of The Affected Factors:Multiple Center Investigation

Evaluation of Quality of Life Pre and Post Interventional Therapy inPatients with Primary Hepatocellular Carcinoma and Analysis of theAffected Factors: Multiple Center InvestigationPostgraduateZhao JianboTutor profLi YanhaoABSTRACTBACKGROUND: Interventions] therapy (IVT) can effectively increase the survival time of the patients with hepatocellular carcinoma (HCC) and was regarded as the preferred non-operation therapeutic method. But in clinical practice, it was usually found that the survival time was prolonged in most HCC patients, meanwhile, their quality of life (QOL) could not be improved, sometimes going down. So the questions are how do IVT affect QOL on earth and what are these affected factors? It is necessary to evaluate HCC patient抯 QOL undergoing IVT, so as to improve their QOL. OBJECTIVE:To evaluate QOL pre and post IVT in the patients with HCC and to analyse the affected factors. Based on the results, to establish the QOL classification of HCC patients. MATERIALS and METHODS: A QOL questionnaire specially for HCC patients (completed by Chonghua Wan) was used to investigate by face to face method in 175 HCC patients undergoing IVT from 3 hospitals of Guangdong province. The investigation time was pre-IVT~ post-IVT 1 and 3 months. The main affected factors of QOL were analysed by univariate and multivariate analysis. The variational curve of QOL during the investigation time was induced and the QOL classification was established. RESULT: The average scores were respectively 115.4+45.1 (pre IVT).. 128.1+28.3.. 129.8+46.4 (post IVT 1 and 3 months) (p