The Clinical And Experimental Study Of Treating Chronic Cholecystitis With Xiangqinglidan Decoction

To search after the effective medicine to Chronic Cholecystitis, the article, on the base of the traditional Chinese medicine, theoretically, clinically and experimentally discusses the cause and the mechanism of the disease, and the treatment of the disease. The article advances a new mechanism of Chronic Cholecystitis that the disease is mainly caused by liver depressed and spleen weakness plus extravasated blood and dampness. According to this mechanism,a new prescription of Xiangqinglidanjian Decoction had been drawn up to treat 46 patients. A Clinical Observation had been carried, the treatment group (46 cases) with Xiangqinglidan Decoction and contract group (40cases) with LidanPian were set up randomly. The two treatments both being taken for two months (one course lasting for one months), have a comprehensive analysis of the effects through the symptom,body sign, tongue condition, pulse condition and gallbladder condition by "B" machine.The result turns out as followings: The treatment group had 73.91% in clinical complete alleviated and 89.13% in total effective rate, superior to contrast group (P<0.05) and the stomach reflection showing distinct improvement. The animal experiment clearly showed that Xiangqinglidan Decoction has the effects on improvement of the bile secretion, increase of bile discharge, improvement of bile system' microcirculation and anti-inflammation etc.Then the conclusion clearly shows that the mechanism of Chronic Cholecystitis ismainly caused by liver depressed and spleen weakness plus extravasated blood and dampness. To relax the depressed liver and invigorate the function of the spleen, improve the function of the gall and relieve the dampness is the important way of curing Chronic Cholecystitis. Xiangjianlidan Decoction has obvious clinical effect to treating Chronic Cholecystitis and the effect has been confirmed on the base of Pharmacology and Materia medica.The article theoretically improves Chinese Medicine' understanding to the Mechanism of Chronic Cholecystitis and offers a new study method. The article also brings a new treatment to the disease and a useful attempt to treating the disease.