| Objective: The aim of the study was to discuss the correlation of regional wall motion abnormality (RWMA) and vascular distribution by comparing the results of RWMA induced by dobutamine stress echocardiography (DSE) and the results of coronary angiography (CAG).Methods: We examined 63 patients with suspected coronary artery disease (CAD) by performing successfully DSE and CAG. DSE was conducted within a week before CAG. According to the 16-segment model formulated by American Society of Echocardiography ( ASE ) ,the left ventricle (LV) was divided into 16 segments and we observed wall motion and contraction for judging the location and regions of segments with RWMA. Also we calculated wall motion score ( WMS ) and wall motion score index (WMSI) .Results: (1) CAG was positive in 48 out of 63,mcluding 38with one-vessel disease,8 with two-vessel disease and 2 with three-vessel disease. We analyzed 32 patients, out of 38 with one-vessel disease DSE was positive ,and evaluated correlation of RWMA and vascular distribution. We deduced the relationship of the certain RWMA for a stenosis involving each of the three major coronary arteries, and the region of LV supplied by right artery was larger than that raised by ASE. (2)The sensitivities for detection 63 with CAD in one-, two- and three- vessel CAD subgroups were 84.2%, 87.5% and 100% respectively. The sensitivities in detecting left anterior artery disease and right artery disease (82.1%, 76.4%) were higher than that in left circumflex disease (33.3%, P<0.05). WMS and WMSI in single vessel disease and multiple vessel disease at peak dobutamine infusion were 19.63 2.02 and 22.2 5. 05, 1.23 0.13 and 1.39 0.32 respectively (P>0.05) .Conclusions: We can estimate the location and extent of stenosed coronary artery by analyzing the correlation of RWMA detected by DSE and vascular distribution. DSE is a safe, convenient and sensitive tool in diagnosing CAD , and hassignificant clinical value in the selection of patients for CAG.
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