| Hypophaeyngeal cancer has become a malignant carcinomas of head and neck which seriously threaten peoples' live and health . Its morbility site is cryptal and the biological characteristics is bad . About 50 - 70 percent of Hypophaeyngeal cancer's cases has metastased when the diease is diagnosed. The . research about Hypophaeyngeal cancer' s lymphatic metastasis characteristics, incidence , influential facters , distribution regular and clinical treatment is little in our country and abroad . So we will invest and analyse about this. It is very significant for patients' treatment and prognosis.Material and methods1. Material; 109 cases of Hypophaeyngeal cancer patients in otolaryngology of The First Affiliated Hospital of China Medical University from 1985 - 2000 were collected. They were all treated by surgical operation. They were not treated by radiotherapy and chemotherapy before operation.2. Methods: According to UICC in 1992 ,all Hypophaeyngeal cancer patients were classified and staged. According to observation after operation all cases were determined their neoplasms' s primary sites and the distributive regions of metastasic lymph nodes. All cases were classifed high middle low differentiation based on pathobiology . By pathologic observation of cervical lymph nodes and the result of follow - up invest the distribution of cervical lymph nodes and the 3,5 year survival rates of Hypophaeyngeal cancer patients.Results1. The incidence of occult nodal metastasis in early stage diease (T, T2) is 45. 8% , and 82.4% in late stage diease (T3T4). The total lymphatic metastasis rate is 74. 3% ( P < 0. 05). 2. Among them , there are 100 cases in pyri-form sinus cancer . The percentage is 91. 7%. The cervical lymphatic metastasis rates of pyriform sinus and posterolateral phorgnyeal wall carcinomas are 74% and 87. 5% (P >6. 05). 3. The cervical lymphatic metastasis rates of high middle low differentiation of carcinomas according to pathobiology are 72. 2% , 67. 6% and 83. 3% ( P > 0. 05 ). 4. The 3,5 year survival rates of Hypopha-eyngeal cancer patients are 51.6% and 33%. 5. The rate of cervical lymphatic metastasis in Level II III is 76.5% , in Level V , VI is 8.6%.DiscussionWhether the Hypophaeyngeal cancer occult cervical lymphatic metastasis or not and the rate is high or low have become a significant facter influenced prognosis. Recently ,with the development of technique of dignosis and treatment, a great progress has been achieved on controlling primary diease , but cervical lymphatic metastasis is main failour reason of treatment.1. The incidence of lymphatic metastasis rate of Hypophaeyngeal cancer and the relation between metastasis and T stage.There is a plent of lymphoduct and blood vessel in different reigons of Hypophaeyngeal . The carcinoma is easy to invade the submucosal. So Hypophaeyngeal cancer is easy to spread and transfer early. This group of material show the rate of lymphatic metastasis in T3T4 is obviously higher than that of in T,T2. and with the progression of diease , the percentage of metastasis is increasing. There is statistic significance between them .2. The relation between cervical lymphatic metastasis and primary sites of carcinoma.Hypophaeyngeal region is divided three different anatomy regions accordingto UICC, they are pyriform sinus postericoid and posterolateral phorgnyeal wall, This group of material show that pyriform sinus carcinoma are 100 cases . The percentage is 91. 7%. The incidence rate of cervical lymphatic metastasis is 74%. Posterolateral phorgnyeal wall carcinoma is 87. 5%. The total lymphatic metastasis rate about these two sites is high (74. 3% ). There has something with lymph drain of Hypophaeyngeal region . Hypophaeyngeal and cervical esophagus have a plant of lymph and their lymph most drain to nodes along vena jugularis interna. The lymph in superior part of pyriform sinus drain superior nodes of vena jugularis interna. That lymph in inferior part of pyriform sinus will cross crico-thyroid membrane to nodes ne...
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