Comparative Study Of Noninvasive Approaches To Detect Coronary Artery Disease In Patients With And Without Diabetes Mellitus

Objective: To evaluate the diagnose value of electrography (ECG), ambulatory elctrocardiography (DCG) and dobudamine stress echocardiography (DSE) for coronary artery disease (CAD) in patients with and without diabetes mellitus. Methods: 61 patients with diabetes and 121 patients without diabetes who underwent corndry angiography (CAG) in our hospital from 1999 to 2002 were retrospectively analyzed. Result: The sensitivities in diagnosis of CAD without diabetes mellitus with ECG. DCG and DSE were 16%, 52% and 90%, respectively. DCG and DSE had a higher sensitivity than ECG (P<0.05), DSE and a velatively higher sensitivity than DCG (P>0.05). whereas, The sensitivities in diagnosis of CAD with diabetes mellitus with the noninvasive approaches were 20%, 75% and 83%, respectively. DCG and DSE had a higher sensitivity than ECG (P<0.05). There's no difference between the sensitivity of DSEand that of DCG. The comperative sensitivities of the 3 noninvasive approaches to dectect CAD in patients with single-vessel Double-vessel and trible-vessel/left main seemed increasinghy high, but between the diabetes group and nondiabetes group. The difference was insignificant (P>0.05). Conclusion: in this study. The 3 approaches to detect the coronarg artery disease in patients with and without diabetes meuitus seemed to have a similar sensitivity. DSE and Holter had a relatively higher sensitiviey and it's well established that the DSE is a safe, feasible noninvasive method for diagnosing CAD. Meanwhile, ECG is proved to be a cheap. Convanvient approach with a realtivitly lower sensitivity. If combined measumerments are employed, they can be widely used in supplementing the shortcoming of each other in diagnosis of CAD.