Correlation Study Between Partial Cutaneous Temperature Variety And MVD In Mammary Cancer

ObjectivesAt present, the prognosis of mammary cancer has not efficacious parameters. Microvessel density ( MVD ) is most meaningful in evaluating prognosis of mammary cancer patients. But in each of research , the liminal numerical value of MVD is different from each others . So it have not been put into clinical application far and wide. The study aims at observing the correlation between partial cutaneous temperature variety of mammary cancer measured through infrared thermography and MVD counted through immunohistochemisty method and providing theory evidence clinically . Probing the mechanism of any abnomal hot area of thermo - patterns.Materials and Methodsthirty two patients with invasive breast cancer were treated by surgery a-lone. Partial cutaneous temperature variety were studied through imfrared thero-mography before operation. MVD were studied by immnohistochemical S - P technique, compare these two value and compare them with fifteen benign tumour.ResultsThe theromopatterns of breawt carcinoma is not symmetrical and there are abnormal hot plot and abnormal vascular pattern, the temperature difference ofthe tumor and its symmetrical location (AT) and MVD are both significiantly higher than benign tumor, we showed an association between highAT and high MVD. There also has an significiantly association between AT and histological grade.CondutionIt have been years of time Since Lawson applied thermo - patterns into diagnosis of disease, Infrared thermography is one of the clinical methods used for detection of breast tumors The principal of infrared thermography is converse the heat sigmal ( infared ray that the body emit ) into electricity signal through a energy conversion element, then simulate the multicolor image and reflect the iota difference in temperature. Abnormal thermo - patterns of the breast is the reaction of the breast skin temperature under the condition of abnormal metabolism and tumor angiogenesis ( TA). This artical suggests that the main causation of hot plot in themo - pattern lies in vascularization and angiogenesis. AT have sig-nificiant correlation with MVD, MVD is most meaningful independent index in evaluating prognosis of breast cancer patients. Thus AT maybe has potential prognostic value for breast carcinoma.Infared thermographic examination is an ecnomic, simple, harmless ,painless and higher accuate for the breast screening and a supplement method for the clinical diagnosis. It also needs more study about the relation of temperature and survival time, the temperature variety checked through infrared thermographic examination should incorporate other factors into markers for the indication of e-valuation of prognosis.