Research On The Application Base Of Minimally Invasive Transmyocardial Laser Revascularization

Transmyocardial laser revascularization(TMLR), which creating holes in the lack blood area of myocardium by laser to improve the state of myocardial ischemic through leading the blood to it and therefore to achieve the purpose of therapy. Experiment studying discovered that laser creating holes would produce thermal injure to some extent to the tissues around holes, and the degree of thermal injure would touch the effect of therapy directly. So understanding and mastering the action rules of laser and myocardium tissues, looking for the relation of thermal injure and laser parameters have significant meaning to the clinical applicationof TMLR, it also has referenced values to the reseach on biomedicine and photonics.The paper has made some analyse and study on the mechanism of TMLR and manking holes in myocardium by the interactional disciplinarian of laser and myocardium tissue. At the same time, it made some contrast and analyse on the excellency and disadvantage of kinds of laser holes by the require of TMLR. This paper also studied the international disciplinarian of laser and myocardium tissue by Diffusion Approximation method, First-order Scattering method and Monte Carlo method, which include absorption coefficient ua, scattering coefficient us and the anisotropy of scattering g. We discussed the infection of these parameters have made to laser photons transmission and distribution in myocardium. A number of quantitative calculate also in the area of our research. Finally, the result of our study indicates: long wavelengh long-infrared lasers(eg. CO2 laser =10600nm, Er:YAGlaser =2940nm) are the perfect choice of TMLR.We have made some attempt on TMLR with computer simulation technology. These attempts would provide referenced values to the reseach on digital vitual somatology and laser medicine and biology .