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Clinical Analysis Of Surgical Therapy Of Cardia Carcinoma

Posted on:2005-11-10Degree:MasterType:Thesis
Country:ChinaCandidate:Y ShiFull Text:PDF
GTID:2144360125450568Subject:Surgery
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Cardiac carcinoma is defined as the tumor which originates from or locates in the range of 2cm below the mucosa borderline of the stomach and esophagus.Its etiology is different from most gastric carcinoma and has no obvious relationship with Helicobacter pylori (Hp) infection. The cardiac carcinoma is highly malignant and has worse prognosis compared with the malignant tumors of the same stage in other position of the stomach. Due to the specific location of the cardiac carcinoma, there are many choices to the operation incisions and approaches of its radical operation. So cardiac carcinoma become the heated topics of the recent surgical study.We analyse in retrospect 162 patients with cardiac carcinoma hospitalized during the period from 1996 to 2004 in the China–Japan union hospital and the first affiliated hospital of JILIN university.We make the following results from the retrospective analysis of the clinical characteristics of the 162 patients:1 Comparative analysis of the basic clinical data of the patients: (1)Male patient is more than female in this group, and the proportion of male and female is 6.4:1. (2) The common ages of the cardiac carcinoma patients are from sixty to seventy years old,and the mean age is 60.7 years old.(3)The patho-logical type of this group is mostly low differentiation adenocarcinoma which is 57.30 percent of the whole cardiac carcinoma patients. (4)Stage IIIA is the most commonest clinical pathological stage of this group, and it's 31 percent of the whole cardiac carcinoma patients. 2 Application of anastomat in the radical operation of the cardiac carcinoma: (1) In the left-chest group, the operative time of applying simply anastomat is 262.9± 60.8 minutes, while the time of anastomosis by hand is 320.8± 62.9 minutes.The operative time of applying simply anastomat is obviously shorter than that of anastomosis by hand(P< 0.05). (2) In the left-chest group, the mid-operative bleeding volume of applying simply anastomat is 327.5± 165.8ml , the bleeding volume of anastomosis by hand is 495.0± 195.0.The mid-operative bleeding volume is obviously smaller than that of anastomosis by hand (P< 0.05). (3)In the left chest group, the positive rate of post-operation incisal edge with anastomat is 5.4%, while that with anastomosis by hand is 19.8%, The positive rate of post-operative incisal edge is obviously lower than that of anastomosis by hand (P< 0.05). (4) The incidence rate in stoma fistula, stoma stenosis, esophagitis reflux has no difference between applying anastomat and anastomosis by hand ( P> 0.05). 3 Contrast of the various operative routes: various operative routes have no obvious differentia in the operation duration,positive rate of the postoperative incisal edge,the clearance number of the lymph nodes,postoperative hospitalized time and the total hospitalized fee. 4 The function of shortening postoperative exhaust time of acusector: the patients apply -ing acusector have no discrepancy in postoperative exhaust time compared with those without applying acusector( P> 0.05). 5 Post -operative survival time of the patients with radical operation of cardiac carcinoma: (1) five-year survival rate of this group patients is 8.8 percent after the radical operative, which is obviously lower than that of gastric carcinoma in a whole.(2) we do the statistical work of the postoperative survival time in the following aspects:the operative route and the clinical pathological stage. In the clinical pathological stage,the postoperative survival time of stage III is clearly shorter than that of stage I and stage II(P< 0.05),while there is no discrepancy in the operative route .We can draw the following conclusions:(1)Male patients are more than female. The common ages of the cardiac carcinoma patients are from sixty to seventy years old(42.6 percent), and the mean age is 60.7 years old.The most common pathological type is low differential type.The most common clinical pathological stage is ⅢA.(2)The application of the anastomat has marked effec...
Keywords/Search Tags:Cardiac carcinoma, surgical therapy
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