Clinical Analysis On Mediastinal Lymph Nodes Metastasis In Lung Cancer

Objective To investigate the clinical rule and characteristics of lymph nodes metastasis in lung cancer,and to provide evidence for lymph node dissection. Methods 105 patient with lung cancer were retrospectively studied, all patients received completely resection plus systemtic lymph node dissection according to the mapping system developed by Naruke. Results Total 801groups of lymph nodes were dissected, the metastatic rates of N1 and N2 were 15. 9% and14. 9%, respectively. There was not significant difference of lymph node metastatic rate among different diameter tumors. The N2 metastatic rate of squamous-cell carcinoma, adenocarcinoma , large-cell and small cell carcinomas wasl3.0%, 31.8%, 33. 3%and50 %, respectively. The lower differentiation of tumor , the higer incidence of N2 metastasis. These skipping N2 were located in 2, 3, 4, 5, 7group respectively. Furthermore, there were often metastasis to the nonregional parts of the mediastinum. Tumor in lower lobes were more likely to spread to the nonregion mediastinum than tumor in upper lobes did. Conclusion Lymph nodal matastasis of lung cancer show characteristics of multiple and solitary. Therefore systemic lymph node dissection ought to performed routinely in thoractomy for lung cancer expect high differentiated squamous cell lung carcinoma in stage T1.