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A Preliminary Study On The Anti-cancer Effect Of Northeast Water Chestnut And Its Mechanism

Posted on:2005-09-17Degree:MasterType:Thesis
Country:ChinaCandidate:F J QiaoFull Text:PDF
GTID:2144360125950844Subject:Environmental Health and Occupational Health
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Northeast Water chestnut is a hydrophillic plant of the water chestnut family, , it is also called ling Water chestnut and it has recorded in the grand traditional Chinese medicine dictionary and Chang bai mountain plant. The plant is also recorded in sanitary board category criterion , There are plenty of resources in the southern and northern part of china The northeast water chestnut studied in this article is gathered in Da an county ji lin province. It is appraised by professor fan shao Bo in jilin agriculture college .literature report : Water chestnut has a function of anticancer ,its stem and meat play a function in elimination summer ,allay a fever ,get rid of worrying ,relieve thirsty ,beneficial breath ,healthy spleen ,anticancer ,strong body ,It can cure skin ulcer stomach canker and papilla splint .Literature report its seed alcohol solution have certain degree anticancer active .In the early 60s of last century A Japanese scholar studied and indicated ;the experiment prove Ling have a better function in anticancer ,in body and out of body .Domestic scholar Zhang Yan Ling and sang Li Hong of shan Dong medical college have done experiment in body on anticancer activity .the northeast water chestnut was extracted by different way in center laboratory public health college Jilin university .The experiment include anticancer active filtration of in body and out of body and it induces liver cancer cell apoptosis and enhance small mouse immunity function and direct cell poisonous effect molecular mechanism experiment study ,it provides a certainty thereunder for the sake of exploitation new medicine with cure and assistant cure cancer .The another name for northeast water chestnut is water chestnut .water chestnut is food therapy good food resound china and foreign countries .It tastes delicious ,tender and juicy and nutritious ,It is reported that through water chestnut meat contains 24% starch 5.9% protein 0.5%fat ,glucose ,vitamin c ergot ,steroid four see below and calcium phosphorus iron and other elements .therefore water chestnut take on function of improve the health helpful breath repair intestines stomach .The research indicate : Water chestnut has the extraordinary efficacy to anticancer .water chestnut was regard bases manufacture a sort of stir medicine bound anticancer medicine-WTTC ( 9g semen coicis,9g wistarin ,9g fructus , 60gwater chestnut ,water fry profess).Nowadays the water chestnut is applied to esophagus cancer ,adenoma uterine cancer as the supplementary therapy .It is discovered that grain alcohol lixivium of water chestnut take on anticancer effect with the intestine filtration experiment in artemisia ascites cancer .medicine expert bake many of diet therapy invigorant :or example new water chestnut juice water chestnut honty tea water chestnut powder porridge and so on which have been put to market .they are popular with people because of anticancer effect of water chestnut outstanding .Nobody have studied about northeast water chestnut weather in chemistry or pharmacology action and in mechanism of action .so set up this research problem ,this article is based on study anticancer experiment of northeast water chestnut and preliminary in inquire into its mechanism of anticancer .It provide a degree foundation for exploitation new medicine .The experiment include follows several side studying work and result:One: Body side choose cell multiplication restrain experiment and dyestuff repel way observe northeast water chestnut anti rat liver cancer H22 cell growth effect. Result make known northeast water chestnut maybe restrain H22 cell growth and its IC50 is 13ug/ml and take on concentration comply with change trend.intestine choose H22 cell tumor vaccinate small rat back limb to observe cancer growth size change .Its rate of inhibition tumor is 47% when pour stomach crude medicine quantity is 26.25g/kg weight body weight.Above –mentioned experiment result showed that northeast water chestnut take on anticancer action and its anticancer active boost up in th...
Keywords/Search Tags:Northeast water chestnut, Tumor, Effect and its mechanism
PDF Full Text Request
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