Coagulation Changes After Severe Head Traumas Department Of Neurosurgery, The Second Affiliated Hospital

ObjectiveTo study coagulation changes and clinical characteristics after severe head traumasMethodsThe blood coagulable data of 26 patients with severe head traumas were detected. The data include Activated partial thromboplastin time(APTT), prothrombin time(PT), fibrinogen(FIB) and thrombin time(TT) at 1st, 2nd, 3rd, 7th day after traumas, same measurements were done in 14 normal control patients at 1st day after traumas.ResultsAPTT increased at 3rd day after traumas and didnot reach normal level at 7th day. (P<0.05) PT increased at 1st day after traumas and reached normal level at 7th day. (P<0.05) FIB increased at 1st day after traumas and began to decrease at 3rd day, FIB began to reach normal level at 7th day. (P<0.05)Conclusionssevere head traumas can cause coagulation abnormalitics. Extrinstic coagulation pathway reached peak earlier than intrinsic pathway. Patients with severe head traumas had hypercoagulable status in intial time after traumas, and began to decrease at 3rd day, then reached normal status at 7th day.