| Background:Coronary heart disease(CHD) is one of important diseases endangering human being's health. The incidence and mortality rate of CHD are gradually increase in China recently. With technological progress, the internal medicine treatments of CHD have developed rapidly. Gruentzig carried the first therapy of percutaneous transluminal coronary angioplasty(PTCA) in 1977.It ushered in a cardiology new era. Then, percutaneous coronary intervention (PCI) had a great development, and became an important measure in CHD treatment. Recent years, the therapeutic range has became large. The complex, serious patients can be cured, and AMI can be cured with emergency PCI. At the same time, drug and PCI combined accelerate medicine progress.CHD is brought into "XIONG BI" category in Traditional Chinese Medicine(TCM). It's disease mechanism includes six types , which are XIN XUE YU ZHU, TAN ZHUO YONG SAI, YIN HAN NING ZHI, XIN SHEN YIN XU, and YANG QI XU SHUAI, which belong to BEN XU BIAO SHI syndrome. BEN XU includes deficiency of XIN QI XUE YING YANG, and BIAO SHI is that vascular skeletons are blocked by TAN RE, TAN ZHUO, YIN HAN, YU XUE, QI ZHI and so on. In BEN XU BIAO SHI syndrome, the basic is QI XU XUE YU,in the south of china, QI XU TAN YU is also an important syndrome.TCM had success in CHD prevention and cure. But it lost it's advantage when it faced to the PCI rising. The degree in CHD prevention and cure was dropped. Now some TCM hospital had develop PCI, and reinforce the TCM clinic study to PCI patient.With the transformation of the medicinal mode, Quality of Life(QOL) of the Patient was increasing attention. As we know, TCM has not a good curative effect guideline. QOL application in TCM was in seedtime in our country. These study show that QOL is an impersonality estimator to TCM clinic curative effection.There are many studies in the QOL of the patient after PCI. These studies had reported that PCI can improve the QOL of the patient after PCI. But there are few study that TCM can improve the QOL of the patient after PCI, especially randomized, double-blind, placeboo-controlled Trial. Our study will adopt this method, and we fill up this blank. At the same time, we will observe symptoms, heart function indexes of the patient after PCI in this clinic study.Objective:We will observe the TongGuan Capsule's effects to the CHD patient after PCI in symptoms, heart function indexes; discuss the TongGuan Capsule's effects to the CHD patient after PCI with different TCM syndromes; evaluate the TongGuan Capsule's effects to the CHD patient after PCI in QOL index. We pile up clinic data for QOL plan tables. It will promote QOL application in TCM. It develop TCM evaluated system in theory.Method:By using prospective Randomized, Double-Blinds Placebo-Controlled study, we observed 59 CHD patients who treated by PCI in Guangdong provincial hospital from 2004-9 to 2005-1. According to Randomized table we drive the patients to the trial group(TongGuan Capsule + western medicine) and the control group(placebo + western medicine). On the day before PCI and in the month after PCI we observe the CHD patients in TCM symptoms, heart function indexes, the 36 items short form of health survey ( SF-36) and the Seattle angina questionnaire (SAQ) . The data putted into computer, and Statisticed by SPSS11.0.Result:Respectively compared patients' indexes correlation on TCM clinic syndromes in two groups' after treatment with before treatment, the trial group's general efficiency rate is 97%, the control group's general efficiency rate is 85%, TCM clinic syndromes have been obviously impoved, which exists notable statistics sense(P<0.05). TongGuan Capsule...
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