Differentiation Of Uterine Myoma And Adenomyosis With Real-time Gray-scale Contrast-enhanced Ultrasonography

Objective: To investigate the value of real time gray-scale contrast-enhancedultrasonography in differentiation of uterine myoma and adenomyosis.Methods: Thirty-one patients with thirty-four uterine lesions were examined by realtime gray-scale contrast-enhanced ultrasonography(CEUS), including 23 cases ofuterine myoma and 8 cases of adenomyosis. The results of CEUS were compared withthose of conventional ultrasound and pathology.Results: After injection of Sonovue, all lesions were enhanced on real-timeultrasonogram. Three patterns of enhancement were observed according to dynamicenhanced model : peripheral net pattern, synchronous enhanced pattern andslow-moving to centripetal pattern. The peripheral net pattern was mostly shown inuterine myoma, synchronous or slow-moving to centripetal enhanced pattern wasmostly shown in adenomyosis. Time to peak intensity, peak signal intensity , 150second signal intensity and enhanced range of adenomyosis were significantly higherthan those of uterine myoma.Conclusion: real time gray-scale contrast-enhanced ultrasonography is useful for thedifferentiation of uterine myoma and adenomyosis.