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The Comparative Study Of Contrast-enhanced Ultrasound And Dynamic Contrast Enhanced MRI In Therapeutic Effect Of Percutaneous Microwave Ablation In Focal Uterine Adenomyosis

Posted on:2018-04-17Degree:MasterType:Thesis
Country:ChinaCandidate:Y Y ZhaoFull Text:PDF
GTID:2334330542954063Subject:Medical imaging and nuclear medicine
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[Research Background and Objective]Uterine adenomyosis is a common benign lesion affecting women of reproductive age.Medication treatments and surgical treatments are traditional therapies.Along with the transformation of medical model,the minimally invasive surgery has been gradually known and accepted by people.Ultrasound-guided percutaneous microwave ablation treating focal uterine adenomyosis can obviously reduce lesions.Dynamic contrast enhanced MRI(DCE-MRI)and contrast-enhanced ultrasound are mainly used to evaluate the ablation effect of percutaneous microwave ablation.This paper aims to research and analyze the therapeutic effect of percutaneous microwave ablation in treatment of focal uterine adenomyos by contrast-enhanced ultrasound and DCE-MRI.[Material and Method]From January 2013 to July 2016,42 patients with focal uterine adenomyosis voluntarily underwent percutaneous microwave ablation in the tumor hospital of Liaocheng.Contrast-enhanced ultrasound and DCE-MRI were performed 1-2 days before and after percutaneous microwave ablation.The position,size,blood signals,the volume of lesion and volume of ablated zone were measured,then,according to the formula:the ablation rate = volume of ablated zone/volume of lesion X 100%,to calculate the ablation rate.The ablation rates detected by contrast-enhanced ultrasound and DCE-MRI were analyzed by t test and correlation and regression analysis respectively.[Result]After percutaneous microwave ablation of the 42 cases,the ablated zone showed no enhancement with contrast-enhanced ultrasound and DCE-MRI.Contrast-enhanced ultrasound showed that the volume and ablation rate of ablated zone were(49.0±29.5)cm3 and(91.6±7.1)%.Contrast-enhanced ultrasound examination showed that 3 of the 42 cases were not ablated completely as expected.Ablation rates of the 3 cases were respectively 56.3%?53.7%?49.3%.The residual perfusion area of the adenomyosis underwent additional treatment,according to the enhancement ranges.1-2 days after percutaneous microwave ablation.contrast-enhanced ultrasound showed that the ablation rates of 3 cases were 84.3%?87.4%?92.6%respectively.The volume and ablation rate of ablated zone detected by DCE-MRI were(49.4±29.9)cm3 and(91.9±6.7)%.The results showed that percutaneous microwave ablation had a good therapeutic effect for patients with focal uterine adenomyosis.The alation rates detected by contrast-enhanced ultrasound and DCE-MRI showed high correlation,that is to say that contrast-enhanced ultrasound and DCE-MRI are in accordance in observing the ablation rate.[Conclusion]Contrast-enhanced ultrasound can accurately show the ablation rate of focal uterine adenomyosis treated with percutaneous microwave ablation,which is quite consistent with DCE-MRI.Contrast-enhanced ultrasound has its advantages such as showing if the lesion needs immiedately supplemental ablation.
Keywords/Search Tags:Ultrasonography, Contrast medium, Magnetic resonance imaging, Uterine adenomyosis, Microwave ablation
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