The Diagnostic Significance Of Solitary Pulmonary Nodules With Dynamic Enhanced Multislice Spiral Computed Tomorgraphy Scanning

Objective: To evaluate the blood flow features of solitary pulmonary nodules ( SPN)using dynamic enhanced methods of multislice spiral compulted tomograph ( MSCT),and to investigate its clinical efficacy in differential diagnosis between benign andmalignant pulmonary nodules.Meterials and Methods: Sixty-three patients(forty-eight malignant nodules,sixinflammatory nodules, and nine benign nodules) with non-calcified nodules( diameter < 4cm) were studied with dynamic contrast enhanced MSCT. Theprecontrast density, peak height after contrast enhanced(PH),and the ratio of the PH ofSPN over aorta(S_PH/A_PH) were recorded. Enhacement patterns of SPN were alsorecorded. Patterns of time-density curve (TDC) were analysized .Results: Malignant, benign, and inflammatory nodules showed its different patternsin TDC , PH and S_PH/A_PH ratio of the malignant and inflammatory nodules weresignificantly higher than those of the benign nodules (p<0.01) ,while no statisticaldifference of the PH and ratio was found between the malignant and inflammatorynodules(p>0.01). Precontrast density of inflammatory nodules was significantly lowerthan that of the malignant nodules (p<0.01) .Conclusion: Dynamic contrast enhanced CT can reflect the hemodynamiccharacteristics of SPN and proved to be an non-invasive meaths in the evaluation ofsolitary pulmonary nodules.