| Objective To evaluate the application of diffusion-weighted MR imaging(DWI) in hepatic masses. Methods DWI and measurement of the apparent diffusion coefficient(ADC) were performed in 30 normal cases and 144 patients with 209 liver masses Result (1) The average ADC value of normal liver is (1.42±0.08)×10-3 mm2/s. Distinctive ADC values were found in liver masses. ADCs in patients with liver masses included liver cyst, (4.33±0.25)×10-3 mm2/s; liver hemangioma, (2.43±0.25)×10-1 mm2/s; hepatocellular carcinoma, (1.63±0.08)×10-3mm2/s; liver metastase,(1.78±0.07)×10-3 mm2/s; liver abscess, (1. 18 ± 0. 11) × 10-3 mm2/s; liver cyst echinococcosis, (3.52 ± 0.20) × 10"3 mmVs and liver alveolar echinococcosis, (2.24±0.20) ×10-3 mm2/s. The difference between the average ADC values were significant (p < 0. 05). (2) DWI (b=500 s/mm2) showed higher detection rate(93. 8%) than TSE-T2WI(83.8%), there were significant different between both( x =4. 01, p < 0. 05). conclusion DWI is useful in differentiated diagnosis of liver masses and can improve the detection of liver malignant lesions.It can be one of the routine sequence in the examination. |