Comparison Study Of Cerebral Blood Flow Before And After Mastication Movement In Aged

Masticatory function is one of the important functions of the oral cavity. It not only associated with nutritional intake of the body, growth and development of the oral and maxillofacial area, but also deeply associated with the status of cerebral blood flow. The implementation of the masticatory function depends on the integrity of dentition. Therefore, the restoration of dentition defects plays an important role in the field of brain function research. Liu Hongchen et al. argued that changes of the cerebral blood flow before and after the masticatory movement might play an important role in evaluating the relationship between the oral cavity function and the brain function. This study aimed to study the changes of cerebral blood flow (CBF) before and after the masticatory movement in aged and young by using the transcranial Doppler ultrasonic examination. Objective: To explore the characteristic of CBF change in aged group by comparative study of cerebral blood flow before and after masticatory movement and comparison with those of young group.Materials and Methods: Ten of aged and ten of young composing of 5 males and 5 females with full dentition were chosed as research object. The cerebral blood flow in the middle cerebral arteries were examined with the ultrasonic diagnostic instrument (DWL Multi Dop X1 Transcranial Doppler, Germany) at the temporal window to obtain data of the systolic peak flow rate, the enddiastolic peak flow rate of the middle cerebral arteries. Results were statistically analysis with Repeated Measures Analysis of Variance with the software of SPSS 10.0 Simplified Chinese Version.Results: 1. There was significant difference in the Vs, Vd and Vm at different time points in aged group (P<0.05). The systolic peak flow velocity in the cerebral middle artery was markedly increased after 5 and 10 min of mastication comparedwith those before mastication. This suggests that mastication could apparently elevate the blood speed in cerebral middle artery and add more blood supply to the corresponding cerebral area of aged group.2. ?There was no significant difference in the systolic peak flow velocity rate of blood flow in the cerebral middle artery of the aged group and the young group (F=0.Ill, p>0.05). The average systolic peak flow rate in aged group in all periods examined in this study has no significant diference with those of young group.?There was significant difference in the diastolic peak flow velocity in the cerebral middle artery compared the aged group and the young group (F=4.763, p<0.05). The average diastolic peak flow velocities of the senile in all periods examined in this study were lower than those of the young group.?There was no significant difference between aged group and young group in Vm (F=0.452, p>0.05). The average peak flow velocity of the aged group in all time point was equal to that of the young group.All above suggest that normal masticatory function could relieve the effect of age on cerebral blood flow and the integrity of the dentition should be preserved and restored as far as possible.Conclusion: 1 The Vs, Vd and the Vm 5 and 10 minutes after mastication in both groups were all significantly higher than those before mastication (P<0.05). This suggests that the masticatory movement could elevate the CBF of the CMA and thus increase blood supply of the related cerebral area in aged group.2 There was no significant difference in the Vs ,Vm rate of blood flow in the cerebral middle artery of the aged group and the young group (p>0.05). There was significant difference in Vd in the CMA compared the aged group and the young group (p<0.05). This suggests that normal masticatory function could relieve the effect of age on cerebral blood flow.