| When human body get the effets of various injured factors, it may occueall kinds of damnification.Trauma is the effets of machenic injured factors, thecontious destroy of tissues and function obstruction by the dynamical action.Acute soft tissue injuries always happen in accidents and sports, that leadto the part inflammition reaction, ache, bleeding, edema, function limitted.Modern physic think that because of the nerve reflect, csusing the osmosisincreasing of blood vessel wall, lots of tissue fluid assemble in the tissueclearance;a part of blood stream from the blood vessel, that make the volumeof muscle increase and strain of muscle membrane increase rapidly;becauseof the obstruction of blood circulation, metabolized dysfuction of local tissue,changing of the inner circumstance, tissue lack of oxygen, aggravate the localtissue injury and anemia injury of muscle, oppressing and stimulating thenerve extremity sensor, causing the edema and pang. If we can't eliminate thesymptom, it will be harmful to blood circulation of the limbs, supplyment ofthe nutritic matter and cicatrization after wound or operation. The severersequent will cause skin blue, elevation of skin temperature and serious painwhen limb arthrosis active. And that the limb longtime trig will cause relativeoxygen lack of tissue, shrink of muscle among bone, affect the healing courseof the limb, finally the sequent injury.It's more popular wound sufferer in emergency, how to release thesymptom of them in time and in effect, as tumefaction and pain, still theproblem that the clinical physician often face of. The therapy methods inexistence not only localize in medicine simply, but in union. Despite the acutegentle tissue injury's healing is well, but the medicine remedy in time andappropriate can release the symptom of sufferer soon, avoid the happening ofcombing disease ineffect, quicken the resuming course of sufferer, make themreback to study, work and living as soon as possible.This text choose 98 cases in emergency when March 2004 to March 2006,58 cases are male, 40 are female, they are 18 to 65 years old, average is 38.3yeas old. When they were injuried to be in hospital the time was in 24h,average is 6h. We frame the standards of excluding cases in order to theaffection of other factors : the man who was opening injury or fracture;dislocation and replacement gypsum fixation;damnification with big bloodvessel;flesh muscle ligament and soft tissue entirely rupture, and etc. Thesufferers who were in condition were disparted to trial group and comparisongroup in random,both 2 groups started to treat after being in hospital. thesufferers in trial group were gived half Mannitol(20%Mannitol 125ml tid.)and Sodium Aescinate(10mg be in 0.9%N.S 250ml qd.) drop, the sufferers incomparison group were gived Mannitol(20%Mannitol 125ml tid.) drop, bothtwo groups were gived traditional physics therapy(ice block cold and kneadthe suffering part tid.). The doctor dynamic observd the guideline of skinappearance, colour, circumference diameter, pain etc. of the suffering part, andthe combing disease after remedy in the 2nd day, 4th day, 6th day.The sufferers in trial group had a great progress with comparison group,details as follows: every guideline of all the sufferers of two groups descendedafter treatment, in the 2nd day, there was no distinct effect in the guideline(p>0.05) in comparison;in the 4th day, the treat effect had a distinct effect(p<0.05);in the 6th day, there was a great prominence in the guideline (p<0.01)in comparison. And in total time of tumefaction and pain that vanished, thesufferers in trial group had effects. The symptom of pain had vanished afterthe symptom of tumefaction had vanished of every sufferer, there was nophenomenon that the symptom was not according to sign happened, 3sufferers in trial group had a bad reaction, only 2 cases had affection onstatistical data.The emphasis of treatment is to control inflammition reaction andeliminate edema. In treatment, the author choosed the medicine thatantinflammation and antitumefaction often used, assit to cold therapy.Physical therapy and cold therapy'application are abroad increasingly,and had a prominent effect for assistant therapeutics. Physical therapy canchange the passing character of biologic membrane, increase the intensity ofthe blood vessel wall, decrease the osmosis of the cell membrane, reduce themore effusion, accelerate the elimination of tumefaction. Local cold therapycan arose blood shrink of the affected part, decrease the circulation of theaffected part, these can do well control to bleeding and congestion, so cancontrol the edema in the inflammation course.The dehydration and diuretic(mannitol) take effects of impacting thefiltration of glomerular and the reabsorpbtion and secretion of theglomertubular to make the the swelling tissue dehydrate and decompress, cutoff the vicious circle, also to accelerate the eduction of maleficent matter ofthe injuried tissue, improve metabolic fuction, acceleratethe the healing ofwound. But the mannitol has a bad possibility that may cause the ARF, so weshould pay attention to the the usage and dosage.The drug function of Sodium Aescinate is to resist effusion and increasethe strain of vein. It has the effects of eliminate tumefaction, resistinflammation and improve blood circulation.In conclusion, via this trial we discover that the united application of halfmannitol and Sodium Aescinate had a prominent effect, and had a longprocess, can not arose the turbulence of water and electrolyte, had no otherbad reaction. so we think it can apply in the treatment of acute gentle tissuedamage abroad.
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