The Clinical Analysis Of Cardiac Function Of Liver Cirrhosis Research For 27 Cases

Because of the circulation system of hepatocirrhosis patientsmaintaining special hypertension status, the abnormity of bloodcapacitance distributing and the level of vaso-active substances , theturbulence of nerve-humor adjustment and the decline of peripheralvascular resistance ect, all these induce the abnormity of myocardiumstructure and Electrophysiology, the dysfunction of autonomic nerveand also do harm to the systolic and diastolic function of cardiacmuscle. This harm is potential, it isn't obvious at resting, but at stress(pathological or physiological) the harm to the contraction of cardiacmuscle will appear. This phenomenon is called cirrhoticcardiomyopathy. As the effective method to cure liver failure which iscaused by all kinds factors. Liver transplantation and TIPS maybebecome the stress factors that induce cardiac insufficiency, even heartfailure of those patients after Liver transplantation. As it is reported,7.3% paitents after Liver transplantation died by heart failure, so it isvery important to screen the cirrhotic cardiomyopathy beforeoperation and protect heart function during the preparation ofoperation. ObjectiveTo study cardiac function of liver cirrhosis patiens and therelationships between cardiac function and liver function, histories,diameter of portal, ascites volume, pathogeny, sexual, transaminase,symptom, liver cancer, ionic turbulence.Materials and methods27 liver cirrhosis patients wihch is slected from NO1 hospital ofjilin university from August 2000 to January 2006 as the study group,and 25 persons which are random selected when they get the healthyexamination from September 2005 to January 2006 as the controlgroup. The two groups both have done such examinations as liverfuction, blood ion, colour ultrasonography of abdomen, Dopplerechocardiography.ResultsThere was a significant difference between the E/A of livercirrhosis patients and that of control group (P<0.05);There was asignificant difference between the E/A of Child A liver cirrhosispatients and that of Child B and Child C liver cirrhosis patients. butbetween the E/A of Child B liver cirrhosis patients and that of Child Cliver cirrhosis patients there wasn`t a significant difference. It was asignificant difference between the E/A of above 5 years course ofdisease liver cirrhosis patients and those of below 1 years livercirrhosis patients. but between the E/A of 1-5 years course of diseaseliver cirrhosis patients and those of above 5 years there was nosignificant difference. There was a significant difference between theE/A of the diameter of portal above 14mm liver cirrhosis patients andthat of below 14mm liver cirrhosis patients.ConclusionThe diastolic function of liver cirrhosis patients were reducedcompared with control group (P<0.05). There are positive relationsbetween the diastolic function of liver cirrhosis patients and liverfunction, course of disease, diameter of portal, while there are noobvious relations between the diastolic function and ascites volume,pathogeny, sexual, transaminase, symptom, liver cancer, ionicturbulence.