The Prevalence And Influential Factors Of Abnormal Glucose Regulation In Patients With Coronary Artery Disease

Objective: Abnormal glucose regulation embraces diabetes mellitus, impaired glucose tolerance, hyperglycemic state, and so on. Most deaths in persons with diabetes mellitus result from accelerated cardiovascular disease (CVD) and mortality attributable to CVD is increased 1.5- to 4.5-fold. Diabetes mellitus, impaired glucose tolerance (IGT), especially 2-h post-prandial glucose, had been identified as independent risk factors for CVD susceptibility and mortality. Overseas evidence accumulated that IGT hyperglycemia may play a role in atherosclerotic disease development and progression, controlling IGT hyperglycemia can reduce the incidence and mortality of cardiovascular disease. In these years, with the pathological physiology and clinical meaning of fasting plasma glucose and 2-h post-prandial glucose developing, we purported that in high blood glucose diagnosis, in the forecast of cardiovascular events, cardiovascular mortality and risk of death, 2-h post-prandial glucose is better than fasting plasma glucose. The Euro Heart Survey engaged 110 centres in 25 countries demonstrated that only 42% of the patients had normal glucose regulation, 36% had impaired glucose regulation and 22%...