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Immune Responses Of Graft Jejunums And MLNs During Acute Rejection In Small Bowel Transplantation Of Rats

Posted on:2007-11-14Degree:MasterType:Thesis
Country:ChinaCandidate:J LiuFull Text:PDF
GTID:2144360185470824Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objectives1. To investigate the phenomenons of apoptosis in the graft jejunums and its MLNs in rat small bowel transplantation and to describe its developments.2. To determine the expression of MAdCAM-1 and the level of IFN-γ mRNA level in the graft jejunums and its MLNs in rat small bowel transplantation and to describe its significances.3. To compare immune responses of the graft jejunums and its MLNs in rat small bowel transplantation.Methods1. Animal model. Heterotopic small bowel transplantation was performed with Wistar/A donors and F344/N (RT1~1) recipients. Bowel...
Keywords/Search Tags:Small bowel transplantation, acute rejection, schem-ia/reperfusion, MLNs, apoptosis, MAdCAM-1, IFN-γ
PDF Full Text Request
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