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Evaluation Of Ischemia Modified Albumin In The Early Diagnostic Value Of Acute Coronary Syndrome

Posted on:2007-01-02Degree:MasterType:Thesis
Country:ChinaCandidate:L ChenFull Text:PDF
GTID:2144360185471346Subject:Medical cardiovascular disease
Abstract/Summary:PDF Full Text Request
BackgroundAcute chest pain suggestive of unstable angina (UA) or acute myocardial infarction (AMI) accounts for about six million hospital admissions per annum in the USA. Only 17% of these are finally diagnosed as acute coronary syndrome (ACS). The correlative reports are less about it in china now. But along with improved life condition and ageing of the population, coronary atherosclerotic heart disease has become common disease hazarding people's well. ACS is one kind of acute syndrome belonging to coronary atherosclerotic heart disease, it includes UA, ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation myocardial infarction (NSTEMI). Cardiac acute ischemia is the most commom mechanism underlying ACS that, when prolongs, may lead to myocardial damage and cell death. But patients with acute chest pain suggestive of ACS present with a heterogeneousarray of condition, including non-ischemia chest pain (NICP), transient myocardial ischaemia, UA, NSTEMI and STEMI, diagnosis of ischemia is difficult in these patients. Particularly those with uninterpretable baseline ECG, normal ECG during pain, or without evidence of myocardial necrosis. None of the traditional clinical variables, 12-lead ECG, biochemical markers of necrosis, and imaging techniques can be considered a true "gold standard" for the diagnosis of cardiac ischaemia. Although cardiac ischaemia is highly probable in the presence of ST segment or T wave changes, regional wall motion abnormalities or myocardial...
Keywords/Search Tags:acute coronary syndrome, ischemia modified albumin, cardiac troponin I, electrocardiography, sensitivity, negative predictive value
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