Biomechanical Study Of Calcium Phosphate Cement In Vertebroplasty

Osteoporotic vertebral compression fractures (OVCFs) caused by severely osteoporosis, have resulted in the progressive spinal kyphosis and changed the biomechanical environment, and OVCFs had an adverse effect on quality of life. The traditional treatment were bed rest, medications, calcium, vitamin D and so on. However, surgical interventions were inefficientive because of the osteoporosis and out of condition. The internal fixations or screws were easy to loose, migrate and result in other surgical complications.Kyphoplasty (KP) and vertebroplasty (VP) are attentioned for their perfect curative effect and low complications. At the present time, the filler used in the KP & VP have some disadvantages. In current study, we designed an animal bone defect model to simulate the biomechanical environment of osteoporotic vertebral fractures. After ovariectomized bilaterally for three months, the female mature goats were drilled in the perpendicular direction to center of the sagittal plane of the vertebra in vivo. The feasibility of calcium phosphate cement for VP & KP with the model in biomechanics were evaluated.PART I The development of an bone defect animal model for vertebroplasty ex vitroObjective To develop and evaluate a new biomechanical animal model for filler used in vertebroplasty and kyphoplasty. Motheds 40 lumbar vertebras harvested from ten fresh mature female goat cadavers were evenly assigned to one of 5 groups. 4 groups were drilled in the perpendicular direction to center of the sagittal plane of the vertebra, with the different drills,?2.0mm,?4.0mm,?6.0mm,?8.0mm. The left intact vertebras...