| Background Keloids are benign, proliferative dermal collagen growths that represent a pathological wound-healing response to skin injury in susceptible persons. They are thick scar tissue of human skin, which have escaped the boundaries of the original wound to invade the surrounding normal skin. Although keloids are common among the darker pigmented races, but the epidemiology of keloids in general is variable. The rported incidence of keloids in the general population ranges from a high of 16% among the adults in Zaire to a low of 0.09% in England. A number of hypotheses such as high skin tension, hypoxia, endocrine dysfunction, fatty acid, autoimmune and genetic hypotheses have been proposed in the past to explain the keloid phonomanon. Sizeable clinical case collections of keloids have been compiled in some countries and regions, but there are limited data on Chinese patients with keloids. The purpose of our study was to explore the epidemiologic and clinic aspects of keloids in Chinese patients.Methods A total of 550 patients with a male/female ratio of 1:1.12 were enrolled and statistical analysis and heritability were performed using EPI INFO 6.0, SPSS 13.0, and the Falconer method.Result ①The age of onset ranged from 1 to 79 years. A peak age of onset was seen between 10 and 30 years for both males and females. The mean ± SD age of onset was 22.61 ± 12.34 years. The difference between the mean age of onset in males (22.05± 11.10 years) and...
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