Improvements On The Immunocytochemical Techniques And Quantitative Study On The Relationships Among FAS, P63 And Apoptosis In Lung Carcinoma

BACKGROUND AND AIMSlung cancer is one of the most frequent malignant tumors. From the middle of the 20th century, the morbidity and mortality of it are growing rapidly. Although there have been being new and advanced techniques and treatments, the prognosis of lung cancer is not very well-80% of cases getting final diagnosis are in the middle or advanced stage and 5-year survival rate is only 14%. Therefore, effective methods for the early diagnosis are very important and necessary. And deep research into the carcinogenes and development of lung cancer is of great significance to the early diagnosis, detection of metastasis and judgment of prognosis of lung cancer.exfoliative cytological examination plays an important role in early diagnosis of lung cancer. The routine staining technique on cell-smear has its own limitation when the smear is observed under light microscope. Misdiagnosis can be made by using it for those cases which are difficult to judge. While the immunocytochemical technique can help doctors make differential diagnosis to these cases and solve the problems which are hard to make sure in cytology. At present, the immunocytochemical technique can not be used widely in clinical pathology because of its own shortage. For instance, the smear is easy to take off from the slide. So, we analyzed some...