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Studies On The Chemical Constituents Of Ophiopogon Japonicus

Posted on:2007-08-02Degree:MasterType:Thesis
Country:ChinaCandidate:H B JiangFull Text:PDF
GTID:2144360185493774Subject:Medicinal chemistry
Abstract/Summary:PDF Full Text Request
This dissertation consists of two chapters. The first chapter reported the extraction and the identification of chemical constituents from the tubers of Ophiopogon japonicus, which is used as a traditional medicine in China. Forty-one compounds were isolated from the ethanol extract of the tubers of 0. japonicus, through repeating silica gel, Sephadex LH-20 column chromatography. Among which, the structures of twenty-seven compounds, including four new homoiso-flavonoids, were identified by the spectroscopic and chemical evidences. Other 3 compounds was got from this plant for the first time. The 27 compounds were listed as below:(1)5,6,7-trihydroxy-3-(4'-hydroxybenzyl)chromone(new)(2a)5,7-dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one(new)(2b) 5,7-dihydroxy-6-methyl- 3-(4'-hydroxybenzyl)chromone(4)5,7-dihydroxy-3-(2',6'-dihydroxy-4'-methoxybenzyl)chroman-4-one(new)(5a)5,7-dihydroxy-6,8-dimethyl-3-(3',4'-dihydroxybenzyl)chroman-4-one(new)(5b) 5, 7-dihydroxy-3-(4'-hydroxybenzyl)chromone(7a)5,7,2'-trihydroxy-6-methyl-8-methoxy-3(R)-(4'-methoxybenzyl)chroman-4-one(7b)5,7,2'-trihydroxy-6-methyl-8-methoxy-3(5)-(4'-methoxybenzyl)chroman-4-one(9a)5,7-dihydroxy-6,8-dimethyl-3(R)-(3'-methoxy-4'-hydroxybenzyl)chroman-4-one(9b)5,7-dihydroxy-6,8-dimethyl-3(S)-(3'-methoxy-4'-hydroxybenzyl)chroman-4-one...
Keywords/Search Tags:Ophiopogon japonicus, chemical constituents, 5,6,7-trihydroxy-3-(4'-hydroxybenzyl)chroman, 5,7-dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one, 5,7-dihydroxy-3-(2',6'-dihydroxy-4'-methoxybenzyl)chroman-4-one
PDF Full Text Request
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