The Observation Of Dynamic Change Of CSEP Na～+-K～+-ATP Ase LDH During ALI

Objective: Investigate the change of evoked cortical potential, Na~+-K~+-ATP ase, LDH during ALI caused by giving oleic acid, discussing the change and mechanism of CSEP ,Na~+-K~+-ATP ase, LDH, which supply basis for clinical treatment. Methods 1: 8 New Zealand long-eared rabbits, equability quantity of male and female supplied by Xinjiang Medical University, compare by itself according to different time 1) the group experiment ago (n=8); 2) experimental group : the experimental group inject oleic acid from parotid vein, and observe the change of CSEP by following indexes: latency(ms), p-p interphase, positive wave values(μV), negative wave values(nV), P-P values(μV) at 30, 60, 90, 120min. Methods 2: 25 New Zealand long-eared rabbits, equability quantity of male and female supplied by Xinjiang Medical University, were randomly divided into 5 groups, as following (n=5): control group, OA 30, 60, 90, 120min group, observe the activity of Na~+-K~+-ATP ase, LDH. Result: 1) Latency: OA 30min group obviously prolongation compared with experiment ago group(P<0.05), OA 120min group obviously prolongation compared with experiment ago group(P<0.05). 2) P-P interphase: OA 30min group obviously prolongation compared with experiment ago group(P<0.01), OA 60min group obviously prolongation compared with experiment ago group(P<0.05), OA 90min group obviously prolongation compared with experiment ago group(p<0,01), OA 120min group obviously prolongation compared with...