Clinical Study On The Law Of Syndrome Differentiation Of Diabetic Cardiopathy

Section 1 Theoretical study Objective and methodsFrom the aspect of Diabetes and Diabetic Cardiopathy, to collect, coordinate, abstract and conclude, discussing the research thought of Diabetic Cardiopathy, Which will provide the academic foundation of treating Diabetes and Diabetic Cardiopathy with experienced prescription.Conclusion and reveal1.The hotspot of Diabetes include the research of epidemiology, pathogeny, the mechanism, treating method, medication and the syndrome. The thought for future research:to introduce the new medical theory, just as factor of inheritance, factor of environment, molecular biology, that may be a opportunity for the development of the diabetic research;to attach importance to the effective compound herb, especially the rule of the buildup of the experienced prescription, quantity-effect relationship, functional target;do not localize in the tache of low down the blood-sugar but from improving the resistance of insulin to prevent and treat the diabetic syndrome, especially the cardiovascular disease, then do a systematic, whole and general research.2. To summarize the TCM research in diabetic cardiopathy, putting forwards the research for the future:from clinical aspect, to attach importance to the standardization and microcosmic of differentiation according to symptom and sign;the diversification and systematization of treatment. In the academic aspect, quoting the modern scientific harvest, for example, there is a close relationship between the endodermis of blood cell, peroxid enzyme receptor γC161T, to go deep into discussing the TCM differentiation essential andtreatment methocK the possible mechanism of the herb of Diabetes;to optimize^ abstract the effective compound herb, building foundation for the new medication.Section 2 Clinical study Objective and methodsTo collect the information of the diabetic patients in ward in our hospital in 1999 to 2004,then coordinate systematically and wholely,looking for the relationship between of diabetes and diabetic cardiopathy;to discuss the characterist of diabetic cardiopathy^ location of disease and evolvement, to confer reference for the TCM diagnosis and treatment for the diabetic cardiopathy.ResultsK Analyzes on the clinical data of 1000 hospitalized diabetic patients.All cases came from wards of medicines, surgery, orthopaedics, specialty of ophthalmology and department of tumor, etc. Cases from ward of medicine took 90. 6% and male ones were equivalent to female ones. The age ranged from 7 to 88 years old and the average age was 60. 5 years old. The course of disease was 1 to 28 years and the average course of disease was 10. 1 years . Every case was in hospital for 3.2 times averagely and the ratio of time aftert time in hospital was 70.8% and the mortality rate was 1.3%.The highest incidence rate of complication was heart disease, and the next in turnwas high blood pressure, nephropathy, hyperlipemia, peripheral nervous lesion, pulmonary infection, arterios fatty liver, cholecystitis and cholelithiasis, retrograde disease of joint, ophthalmopathy, ketosis, cerebral infarction and urinarytract infection, .gastrointestinal infection, derma infection, virosis hepatitis, stomach paralysis, cerebral infarction, kidney stone, anaemia, bone loosen, tumar, etc.The ratio of red tongue and pale tongue was 52.7:47.3. The percentage of dismalbody of the tongue was 33%, and 52.2%, 24.5% in greasy and yellow fur on thetongue and in greasy and yellow fur on the tongue plus greasy and white fur on thetongue. The deficient pulse cases were equivalent, to replete pulse ones. The percentage of deficiency of both the vital energy and yin was 79. 9%,and the percentage of deficiency both the yin and yang was clerosis, n got the highest, and the next in turn was deficiency of qi, deficienc fewer and deficiency of yin and dryness heat was the fewest. As to the location of the disease, the liver got the highest, and the next in turn was kidney, spleen, stomach, heart, lung, bladder, gall bladder and large intestine. Each case deals with 3 to 4 locations of the disease. As to deficiency syndrome, deficiency of yi y of yang and deficiency of blood. As to evil factors, this turns was blood stasis, depressed vital energy, wind and yang, damp heat, damp turbidity, accumulation of dryness, water, phlegm heat, fire, phlegm damp, poison, evil wind, cold and cold turbidity. The percentages of hot natured pathogen and damp natured pathogen were 53. 3% and 32. 9%.2. Analyzes on the clinical data of 528 patients of diabetic cardiopathy Compared with non-cardiopathy group, the diabetic cardiopathy group had significant difference as follows. More female patients, older in age, longer in course of disease and more times for hospitalization could be seen in this group. The youngest age for the coming on age was 22. More complications of nephropathy, nervous lesion, cerebral fraction hypertension and arteriosclerosis could be seen in this group. The incidence of pulmonary infection, urinary tract infection and cholelithiasis was increased also. The deficiency of both yin and yang syndrome got the most in this group. As to the location of disease, diabetic cardiopathy group deal with kidney, heart and lung and non-diabetic cardiopathy group deal with stomach. As to the disease due to asthenia of viscera, diabetic cardiopathy group mainly deal with deficiency of yang and non-diabetic cardiopathy group with deficiency of qi. As to the evil factors, the wind yang, phlegm heat, damp turbidity, blood stasis, dry stagnation and water got the most in diabetic cardiopathy group.Conclusion1 . Patients of diabetes mellitus mainly accepted treatment in the ward of medicine. They could be in hospital of the wards, according to its complications, of surgery, orthopaedics, specialty of ophthalmology and department of cancer, etc There was no gender difference in the incidence of diabetes. Most of the complications were gray-headed diseases but youngster and young adults also could get it. Type 2 diabetes mellitus was the main typeand the death rate was relatively low because of the combined treatment of Chinese medicine and Western medicine. Heart disease was the all-important complication of diabetes mellitus. The main Cache of pathological changes was related to cardiovascular disease, nervous lesion, infectious diseases, metabolic diseases, endocrine diseases, immunological disease and degenerative diseases. Analyze of TCM tongue and pulse showed that it was mix of cold and heat and mix of deficiency and excess. We also found out that blood stasis was the main pathogenic factor and result. The main syndrome type was deficiency of both qi and yin. Deficiency of both qi and yin and deficiency of both yin and yang were the most important leading pathogenic changes in the medium and late term of diabetes. Blood stasis, depression, wind yang, damp heat and damp turbidity were the most prominent evil factors during the course of diabetes mellitus. And stagnancy of qi and blood stasis, accumulated damp^heat and going up of wind and yang were the main pathogeneses of complications, especially for cardiovascular diseases and nervous diseases, of diabetes. Thus regulating qi and blood, eliminating damp and heat and calming the wind of liver were the important keys in the prevention and cure of complications of diabetes. The dryness, fire, phlegm, water and toxin, which sharpened the impaired qi and yin so as to form the vicious circle, were the pathogenic factors that could not be ignored during the course of complications of diabetes.2. Patients in diabetic cardiopathy group had features such as more female patients, older in age, longer in course of disease and more times of being in hospital. In the patients of diabetic cardiopathy, we should pay attention to the advance of come-on age and the complication of heart disease in youthful patients. There was high correlation between diabetic cardiopathy and other vascular and nervous complications. TCM syndrome in diabetic cardiopathy group mainly took on deficiency of yin and yang and the position of disease was mainly related to kidney, heart and lung. The state of illness in this group was serious and had bad prognosis The deficiency of vital qi, more pathogenic products and complex state of illness could also be seen in the diabetic cardiopathy group.