Clinical Investigation Of Coronary Artery Calcification Detected By 64-slice Spiral Computed Tomography On Diagnosis Of Coronary Heart Disease

Objective: Atherosclerosis is the pathophysiologic basis of coronary heart disease (CHD). Accurate measurement of subclinical coronary atherosclerosis should significantly improve the prediction of future cardiovascular events. Histo -pathological and intravascular ultrasound studies confirmed the close correlation between atherosclerotic plaque burden and extent of coronary artery calcification (CAC). Furthermore, CAC detected by multi-slice spiral computed tomography (MSCT) the high sensitivity and non-invasive were made this test potentially useful as a screening of diagnosis CHD. So detection of CAC with MSCT is a reliable method to diagnose CHD. Traditional risk factors assessment only help to predict 60% to 65% of cardiac risk, while many individuals had suffered from CHD in absence of established risk factors. CAC detected by MSCT was a stronger independent predictor of CHD and its predicting activity was more than a sum of all of the traditional risk factors. Cardiovascular calcification is the most common type of ectopia calcification in end-stage renal disease (ESRD). Hyperphosphatemia may play a key role in cardiovascular calcification in ESRD. The correlation between...