A Clinical Study On Tubal Pregnancy Treated With Integration Methotrexat And Traditional Chinese Herb

Objective: To observe the clinical therapeutic of integration methotrexate(MTX)and traditional Chinese herb(TCH ) for tubal pregnancy.To seek a simple,safe and efficient method to cure the tubal pregnancy and preserve fertility.Methods: 62 cases of EP were divided into two groups at random. The treated group with 31 cases was employed MTX single-dose intramuscual injection and TCH (ectopic pregnancy decoction and xiaozheng decoction retention enema).The control group with 31 cases was treated by employed MTX.In the study,to observe the changes of clinical symptoms and signs,the level of serumβ-HCG andthe size of adnexal mass by abdominal ultrasound between the two groups.To compare the time of serumβ-HCG decreasing to normal level,disappearance of the adnexal masses and fluid of retrouterine excavation,the restoration of normal menstruation,the tubal patency,the treatment period of MTX and the side reaction of MTX between the groups.Results:①The success rate of the treated group which was 93.55% was greater than that of the control which was 74.18%.The difference of the two groups was significant(P<0.01). ②The average time of serum β-HCG restoring to normal level which was(15.24 ± 4.66)days,the disappearance time of the adnexal masses and fluid of retrouterine excavation which was(28.64 ± 10.85)days and ( 11.45±3.17) days,the average time of restoring menstruation which was(28.04 士 4.96)days,obviously shorter than those of the control which were respectively (20.48±5.44)days,(44.44 ± 11.59)days,(15.13±4.39) days and(33.43 dr 6.47)days.There were significant differences between the groups(P<0.05).③The tubal patency of the treatedgroup higher than control group(P<0.01).?The treatment period of MTX and rate of the. side reaction of MTX the treated group lower than control group(P<0.05).Conclusions:The therapy of integration methotrexate (MTX) and traditional Chinese herb(TCH) for treating tubal pregnancy not only widen the range of conservative treatment but also promote the absorpton of focus, increase cure rate and tubal patencyrate, preserve the fertility of patient,reduction the treatment period of MTX and relieve the side reaction of MTX.