| Objective:To explore the incidence of DWI abnormalities in patients with TIA which clinical signs and symptoms are associated with the presence of TIA-related DWI abnormalities,and the characteristics of DWI lesions (localization, number, mean volume, ADC, rAI : related averge intensity) were researched. We investigated the characteristics of DWI lesions to distinguish the difference between TIA and acute ischemic stroke.Materials and Methods: A prospective analysis was performed on all patients who entered the Pu-dong New Area People's Hospital during 2005-10 to 2006-4 and who were clinically diagnosed with a TIA and who had also undergone a DWI scan <5 days after symptom onset. Clinical data, conventional magnetic resonance imaging (MRI), and DWI were collected in 39 consecutive patients with TIA and 20 consecutive patients with acute ischemic stroke. The relationship between DWI-detected findings and patients'clinical presentation was then analyzed. Using an image analyzing system, we calculated the ratio of the lesion and corresponding contralateral normal tissue average signal intensity and ADC values which come from TIA and stroke patients were compared .Results: The related focus of TIA were most located at basal ganglia 50%(9/18). Lesions were small (mean volume: 1.29±0.38cm3), and ADC was decreased lightly (rADC ratio: -25.8±9.01%). In all of these cases the DWI clarified the extent or acuity of the lesion compare to conventional MR imaging.The diagnosis of TIA was considered as probable in all DWI+ patients. A multiple logistic regression model demonstrated that TIA duration was more than or equal to 60min, aphasia and motor deficit were independent predictors of DWI lesions.Conclusions: The incidence of positive DWI scans in our study is 38.5% of our TIA... |
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