Detection Of Cognitive Function Of Tic Disorders Childhood And Study Of The Correlation Between Cognitive Function And Dopamine

Background: Tic disorders is a chronic neuoropsychiatric disease characterized by suddent, rapid, recurrent, nonrhythmic, stereotyped motor movements or vocalization. It includes Tourette' s Disorder(TS), Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder, and Tic Disorder Not Otherwise Specified. The incidence of children is high. Studies showed that such kind of patients had cognitive impairment. At the same time, abnormal doparminergic system function had been found in the patients. However, most of the cognitive function studies were focused on TS and relatively rare on other subtypes. Whether there were differences of the cognitive function between the subtypes was unknown. Fourther more, the correlation between cognitive function and serum level of dopamine(DA) has not been demonstrated, and weather neuroleptics damage the cognitive function is unconfirmed. In order to study the cognitive function of children with varied types of Tic Disorder and the change of serum level of DA, the correlation between cognitive function and DA, and whether neuroleptics such as Haloperidol...