The Study Of Cognitive Function In Tourette's Syndrome Comorbid Obsessive-compulsive Symptoms

Objective:To explore the features of cognitive function in Tourette's syndromes with and without obsessive-compulsive symptoms. Method: 127 participants who met the DSM-IV criteria for GTS took part in the study and among whom we assessed using the Yale-Brown Obsessive-Compulsive Scale to screen 49 participants comorbid obsessive compulsive symptom.A series of cognitive tests including Visual Memory Test,WCST, Trail Making Test, Stroop Test ,Verbal Fluency Test and the Yale Global Tic severity scale were applied to the participants .At the same time, a normal control group matched in age and education time were evaluated by the same cognitive tests.Results:The GTS patients' cognitive functions are impaired generally.The performance of Visual Memory Test between GTS alone group and comorbid OCS group has no difference,but is lower than the normal control group.All of the GTS group's (including GTS alone and comorbid OCS)results of Stroop test are worse than the control group except of Stroop-C wrong.As for subgroups of GTS,several items should be underlined such as Stroop-C time, Stroop-CW correct, Stroop-CW wrong,Stroop-CW time, Trail Making Test A wrong, Trail Making Test B time and wrong.The Verbal Fluency Test's results of GTS group are poorer than control group and equal in...