| Cerebrovascular ischemia disease is one of the commonest diseases with high disability and mortality rate in clinical practice. And reperfusion is the main curing method in clinical treatment. However, after a period of time of ischemia, reperfusion would reversely aggravate the state of illness. In recent years, lots of experimental researches have showed that there was a closed relationship between cell apoptosis and ischemic brain injuries. So, thorough researches on the occurrence and mechanism of cell apoptosis after cerebral ischemia reperfusion injury would provide a new means to prevent and cure ischemic brain injuries.Tribulus terrestris refers to the dry, ripe fruit of the plant caltrop. Its main chemical ingredients are saponins, ketone, alkaloid. The gross saponins of Tribulus terrestris(GSTT) was one of the effective group ingredients which was extracted from the whole plant of caltrop. It is a mixture of over 10 kinds of saponins, mainly steroid saponins. It mainly includes furan-strol and spiral-strol. It is a powder and dissolvable in water. Domestic research materials showed that GSTT had the effect of lowering blood pressure and stimulating anti-hypoxia, sheeting blood vessels, lowering cholesterol, inhibiting fat deposition on arteries, myocardium and liver. It also inhibited atherosclerotic occurrence and development. It had positive effects on brain ischemia, lowering blood sugar, showed anti-aging properties and improved sex function. Capsuled preparation of GSTT has been...
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