| Mucopurulent cervicitis is an inflanmmation of the uterine cervix. Recently, many studies showed MPC might be caused by Chlamydia trachomatis (Ct),Neisseria gonorrhoeae (Ng),Trichomonas vaginalis (Tv),herpes simplex virus (HSV),or human papillomavirus (HPV); it might be caused by Mycoplasma genitalium (Mg),Ureaplasma Urealyticum (Uu) and anaerobian too. In foreign countries, many studies have showed screening of Ct in MPC, and had also discussed about Uu. But in this region, the are only few studies on association between the infectious agents (CT,UU,Ng) and MPC. MPC is the most common infection of genitourinary system, the rate of development was higher at present. Although Ct and Ng are the most common organisms of MPC, but in many patients sometimes it is difficult to find out the cause. And treatment is depended on experience, so the treatment is not that effectective. Detection of the pathogens may result into specific therapeutic measures, with varying degrees of success.Objective: To explore the infection of Chlamydia, Mycoplasma, Neisseeria gonorrhoeae, Trochomonas, Candida, Heroes simplex virus and Human papilloma virus in patients acquiring the urogenital infections and study the relevant factor. Cervical secretions were obtained from 419 patients with mucopurulent cervicitis. We detected Ct,Uu,Mg,Mh,Ng,Tv,Gv,HSV-2 and HPV by Culture and PCR methods. At the same time, we have kept record for survey, including the age, sex, marital status, the culture level and the infection sources, ect, which are relevant to the MPC infection.Results of test indicate: (1) Of 419 patients with MPC, the cause was found in 372 (88.78%) patients. Of the 372 patients, the percentage of positive tests for CT was21.00% (88/419),Mg 9.31% (39/419),Uu 25.30% (106/419),Mh 0.48% (2/419),Ng 12.17% (51/419),Gv 3.58% (15/419),Tv 3.81% (16/419),HSV-2 7.16% (30/419) and HPV 5.97% (25/419). Among them, the percentage of Uu was significantly higher. In the control group, the positive rate of secretion was 38.68% (41/106), Uu was 33.45% (36/106), Among the HSV was 1.88% (2/106),the HPV,Ct and Mg was 0.94% (1/106) respectively. The study shows that the coexisting infections rate of two and more pathogen was 9.79% (41/419), the most common pathogens are Ct,Uu,Mg,HSV-2 and Ng. The coexisting infections with three pathogen were found in three cases. Two total pathogen,Ct,Ng,Mg,HSV-2,HPV,Gv,Tv and coexisting infections were statistically significant (P<0.05), Mh and Uu of two groups was statistically insignificant (P>0.05). Clinical features and Epidemiology features of 419 MPC cases ware analyzed.1. clinical features of MPC: (1) 293 case patients who had cervical erosion, recurrence rates were in 98 cases (33.45%). The larger the cervical erosion area, the probability of Uu infection was high, prevalence of infection with each groups with mild, moderate and severe cervical erosion were 20.59%, 28.97% and 54.76% respectively.2. Epidemiology features of 419 MPC patients:2.1 Young people with age group between20-30 was the most common;2.2 Culture performed on school going adlosecent;2.3 Unemployment had the higher chances to get this minfection; 2.3 Distribution is higher in the city region;2.4 Married women had the higher percentage;2.5 non-sexual contact was the most common source of infection.Our conclusion: (1) The Uu had a higher positive expression rate in the MPC patients in the STD out-clinic; (2) There were two or more pathogen exiting in the MPC; (3) Uu positive had nothing to do with mucopurulent secretion; (4) We should pay more attention to the asymptomatic patients; (5) The probability of Uu infection was high with large cervical erosion area; (6) Epidemics and transmitting of MPC was associated with many risk factors. This study provides the experimental evidence for the pathogen, diagnosis and treatment of the MPC, and is helpful in the prevention of STD.
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