Effects Of Glutamine On Patients Undergoing Postoperative Chemotherapy For Gastric Cancer

Objective To study the effects of glutamine on patients undergoing postoperative chemotherapy for gastric carcinoma.Methods 72 cases were randomly divided into experimental and control groups: experimental group, parenteral nutrition with alanine-glutamine(Ala-Gin); control group, standard diet. The determinations made before and after 1 day of chemotherapy: the level of glutamine(Gln) in plasma; the total protein(TP), albumin(Alb), retinol-binding protein(RBP), pre-al-bumin(PA), and transferrin(TFN); the D-lactate, immunoglobumin and T-lymphocyte subgroups; interleukin-1α(IL-1α), interleukin -2(IL-2), interleukin -6(IL-6), tumor necrosis factor-α(TNF-α); Observe the symptoms of vomitus, diarrhea and appetite.Results Compared to control group, the level of glutamine. Alb, RBP, PA, TFN, IgA, IgG, CD4~+ and CD4~+/CD8~+ in experimental groups were increased significantly; the D-lactate in plasma and IL-1α , IL-6 TNF-α were decreased significantly(P<0.05); the loss of symptoms of vomitus and diarrhea. Conclusion The level of glutamine on Patients Undergoing Postoperative Chemotherapy for Gastric Cancer decreased; The immunonutrition in post-operative...