An Exploratory Study Of Botulinum Toxin Type A Efficacy In Treating Migraine With Acupuncture Points Injection

Objective: The efficacy of traditional Chinese medical acupuncture points adopted by injecting botulinum toxin type A (BTX-A), an inhibitor against "migraine generator" identified by our recently research, to treat migraine was investigated, further, and effectivity of that was compared with the method of location sites injected BTX-A used to treat migraine. The frequency, intensity, duration of migraine seizure and concomitant symptoms in mingraineurs were compared between pre-therapy and post-therapy with BTX-A injection, furthermore, between patients injected by BTX-A with acupuncture points and that with location sites. The purpose was to find the much effective method for treating migraine, in addition, probe into the analgesic mechanism of BTX-A and provide a new, safe and effective therapy for treating migraine in clinical practice.Methods: Sixty cases corresponding to the 2004 criteria of diagnosis of migraine amended by the Headache Classification Committee of the International Headache Society (HCC-IHS) were randomly divided into group â…  ( n=30 ) treated with location sites BTX-A injection and group â…¡...