Curative Effect Of Henoch-Schonlein Purpura Treated Mainly By "Zidianqinng" And Study On The Expression Of SVCAM-1 In Serum

Objective: The goal of this clinicial experiment is to observe the clinical effect of ZiDianQing in treating Henoch-schonlein purpura and probe the effect on the level of sVCAM-1 .Methods: 58 patients with HSP were divided into 2 groups openly:the experiment group was 30 cases,the control group was 28 cases.the ZiDianQing treatment was given to the experiment group, the Prednisone treatment was given to the control group, the course of treatment is 30 days.we need to observe 2 courses of treatment.we compared the difference of the time which clinical symptoms' disappearance need and the level of sVCAM-1 in serum before and after treatment between the two group.Result:(1)The curative effects in the experiment group were similar to those in the control group(p> 0.05).(2)The experiment group has an evident improvement in protein in urine,the improvement of other symptoms is no better than the control group. (3)ZiDianQing has no side-effect of Henoch-schonlein Purpura treated by Prednisone.(4)The experiment group can regulate the level of sVCAM-1. the same was true of the control group(p>0.05).Conclusion: ZiDianQing can be effective against the patients' clinical symptoms,especially against protein in urine and decrease the level of sVCAM-1,but it has no side-effect of hormone,so it uses to cure patients of Henoch-schonlein purura long instead of hormone.