A Trial Of Yiqihuoxuetang In Patients With Stable Angina Pectoris

Objective: to study and evaluate the clinical efficiency o Yiqihuoxuetang for the treatment of stable angina pectoris in coronary heart disease(CHD). Methods: The patients brought into the trial were received two weeks' introduction period (include: stopping using anti-angina pectoris drugs, when angina pectoris attacks, using nitroglycerin and recording the location, frequency, duration, degree, the amount of activity inducing angina and dosage of nitroglycerin.).The patients were divided into two groups using one-blind randomlized way. The patients in control group use compound Xin Kang diet and the ones in treatment group use Yiqihuoxuetang. The trival lasted six weeks. Observing and comparing curative effect parameters changes of each group before trial and after trial and evaluating clinical symptoms effect changes between two groups.Results: There were 60 patients who have finished the trial. They ali came from Cardiac centre of Guangdong province hospital of traditional chinese medicine. 30 patients were in treatment group and the others were in control group. After 6 week' s treatment, every curative effect parameters were observed and recorded. Using statistical way, the research results show: There are significant differences in the curative effect parameters compared with the ones before treatment in each group. (P＜0.05) and there are sigificant differences in the clinical symptoms effect change after treatment between two groups. (P＜0.05). The angina pectoris clinical efficacy rate has differences between two groups (P＜0.05) for the treatment group is 90.0% and the control group is 70.0%. There are significant differences in the curative effect parameters (P＜0.05) such as angina pectoris attack times each week, the total dosage of nitroglycerin used each week, the duration of angina attack and so on, but there are differences between two groups (P＜0.05). The total ECG efficacy rate is 76.7% in treatment group and the one is 73.3% in contral group, There are no significant differences in ECG efficacy in two groups. No significant differences in treadmill exercise test (P＞0.05)are showed in two groups, which total efficacy is 68.8% in treatment group and 64.3% in contral group(P＞0.05).Conclusion: Yiqihuoxuetang is effective in treating stable angina pectoris which belongs to qi deficiency and blood stasis in traditonal chinese medicine. It is an effective chinese patent medicine which is betterThan compoud Xin Kang diet in therapy.